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Université de Fribourg

Complementary medicine use during cancer treatment and potential herb-drug interactions from a cross-sectional study in an academic centre

Jermini, Mégane ; Dubois, Julie ; Rodondi, Pierre-Yves ; Zaman, Khalil ; Buclin, Thierry ; Csajka, Chantal ; Orcurto, Angela ; Rothuizen, Laura E .

In: Scientific Reports, 2019, vol. 9, no. 1, p. 5078

Complementary medicine (CM) is used by one third to one half of cancer patients throughout the world. The objective of this study was to describe the prevalence of CM use and the potential for interactions with cancer treatments in an academic oncology centre. A cross-sectional study was conducted among patients undergoing current cancer treatment. Among 132 included patients, 56% had used CM...

Université de Fribourg

Proangiogenic factor PlGF programs CD11b+ myelomonocytes in breast cancer during differentiation of their hematopoietic progenitors

Laurent, Julien ; Faes-van't Hull, Eveline ; Touvrey, Cedric ; Kuonen, Francois ; Lan, Qiang ; Lorusso, Girieca ; Doucey, Marie-Agnes ; Ciarloni, Laura ; Imaizumi, Natsuko ; Alghisi, Gian Carlo ; Fagiani, Ernesta ; Zaman, Khalil ; Stupp, Roger ; Shibuya, Masabumi ; Delaloye, Jean-François ; Christofori, Gerhard ; Ruegg, Curzio

In: Cancer Research, 2011, p. -

Tumor-mobilized bone marrow-derived CD11b+ myeloid cells promote tumor angiogenesis, but how and when these cells acquire proangiogenic properties is not fully elucidated. Here we show that CD11b+ myelomonocytic cells develop proangiogenic properties during their differentiation from CD34+ hematopoietic progenitors and that Placenta Growth Factor (PlGF) is critical in promoting this education....