Université de Fribourg

Polymer-coated gold nanospheres do not impair the innate immune function of human b lymphocytes in vitro

Hočevar, Sandra ; Milošević, Ana ; Rodriguez-Lorenzo, Laura ; Ackermann-Hirschi, Liliane ; Mottas, Ines ; Petri-Fink, 6 Alke ; Rothen-Rutishauser, Barbara ; Bourquin, Carole ; Clift, Martin James David

In: ACS Nano, 2019, vol. 13, no. 6, p. 6790–6800

Gold nanoparticles (GNPs) are intended for use within a variety of biomedical applications due to their physicochemical properties. Although, in general, biocompatibility of GNPs with immune cells such as macrophages and dendritic cells is well established, the impact of GNPs on B lymphocyte immune function remains to be determined. Since B lymphocytes play an important role in health and...