Université de Fribourg

Repetitive activation of the corticospinal pathway by means of rTMS may reduce the efficiency of corticomotoneuronal synapses

Taube, Wolfgang ; Leukel, Christian ; Nielsen, Jens Bo ; Lundbye-Jensen, Jesper

In: Cerebral Cortex, 2014, p. -

Low-frequency rTMS applied to the primary motor cortex (M1) may produce depression of motor-evoked potentials (MEPs). This depression is commonly assumed to reflect changes in cortical circuits. However, little is known about rTMS-induced effects on subcortical circuits. Therefore, the present study aimed to clarify whether rTMS influences corticospinal transmission by altering the efficiency of...

Université de Fribourg

Cutaneous mechanisms of isometric ankle force control

Choi, Julia T. ; Lundbye-Jensen, Jesper ; Leukel, Christian ; Nielsen, Jens Bo

In: Experimental Brain Research, 2013, p. 1–8

The sense of force is critical in the control of movement and posture. Multiple factors influence our perception of exerted force, including inputs from cutaneous afferents, muscle afferents and central commands. Here, we studied the influence of cutaneous feedback on the control of ankle force output. We used repetitive electrical stimulation of the superficial peroneal (foot dorsum) and medial...

Université de Fribourg

Subconscious visual cues during movement execution allow correct online choice reactions

Leukel, Christian ; Lundbye-Jensen, Jesper ; Christensen, Mark Schram ; Gollhofer, Albert ; Nielsen, Jens Bo ; Taube, Wolfgang

In: PLoS ONE, 2012, vol. 7, no. 9, p. e44496

Part of the sensory information is processed by our central nervous system without conscious perception. Subconscious processing has been shown to be capable of triggering motor reactions. In the present study, we asked the question whether visual information, which is not consciously perceived, could influence decision-making in a choice reaction task. Ten healthy subjects (28±5 years) executed...