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Université de Fribourg

Cost-effectiveness of drug-eluting stents in elderly patients with coronary artery disease: the SENIOR trial

Bulsei, Julie ; Butel, Thibault ; Varenne, Olivier ; Cook, Stéphane ; Cuisset, Thomas ; Carrié, Didier ; Hovasse, Thomas ; Morice, Marie-Claude ; Sinnaeve, Peter R. ; Durand-Zaleski, Isabelle

In: Value in Health, 2019, vol. 22, no. 12, p. 1355–1361

Elderly patients receive bare metal stents instead of drug-eluting stents (DES) to shorten the duration of dual antiplatelet therapy (DAPT). The SENIOR trial compared outcomes between these 2 types of stents combined with a short duration of DAPT. A significant decrease in the number of patients with at least 1 major adverse cardiac and cerebrovascular event (MACCE) was noted in the DES...

Université de Fribourg

Absorb bioresorbable scaffold versus xience metallic stent for prevention of restenosis following percutaneous coronary intervention in patients at high risk of restenosis: rationale and design of the COMPARE ABSORB trial

Chang, Chun Chin ; Onuma, Yoshinobu ; Achenbach, Stephan ; Barbato, Emanuele ; Chevalier, Bernard ; Cook, Stéphane ; Dudek, Dariusz ; Escaned, Javier ; Gori, Tommaso ; Kočka, Viktor ; Tarantini, Giuseppe ; E.J.West, Nick ; Morice, Marie-Claude ; G.P.Tijssen, Jan ; Geuns, Robert-Janvan ; C.Smits, Pieter

In: Cardiovascular Revascularization Medicine, 2019, vol. 20, no. 7, p. 577–582

Background: The advent of bioresorbable vascular scaffolds (BVS) was considered as a potential improvement in percutaneous coronary intervention (PCI) after the groundbreaking development of drug eluting stents (DES). However, the clinical performance, long-term safety and efficacy of BVS in complex coronary lesions remain uncertain. COMPARE ABSORB, a multicenter, single blind, prospective ...

Université de Fribourg

Comparison of a novel biodegradable polymer sirolimus-eluting stent with a durable polymer everolimus-eluting stent: 5-year outcomes of the randomized bioflow-ii trial

Lefèvre, Thierry ; Haude, Michael ; Neumann, Franz-Josef ; Stang, Karl ; Skurk, Carsten ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Macia, Jean-Christophe ; Windecker, Stephan

In: JACC: Cardiovascular Interventions, 2018, vol. 11, no. 10, p. 995–1002

ObjectivesThe authors aimed to compare long-term data of an ultrathin cobalt- chromium stent with passive silicon carbide coating and an active biodegradable polymer that releases sirolimus (O-SES) (Orsiro, BIOTRONIK, Bülach, Switzerland) with the durable polymer-based Xience Prime everolimus-eluting stent (X-EES) (Abbott Vascular, Santa Clara, California).BackgroundBiodegradable polymer...

Université de Fribourg

Myocardial infarction stabilization by cell-based expression of controlled Vascular Endothelial Growth Factor levels

Melly, Ludovic ; Cerino, Giulia ; Frobert, Aurélien ; Cook, Stéphane ; Giraud, Marie-Noëlle ; Carrel, Thierry ; Tevaearai Stahel, Hendrik T. ; Eckstein, Friedrich ; Rondelet, Benoît ; Marsano, Anna ; Banfi, Andrea

In: Journal of Cellular and Molecular Medicine, 2018, p. -

Vascular Endothelial Growth Factor (VEGF) can induce normal or aberrant angiogenesis depending on the amount secreted in the microenvironment around each cell. Towards a possible clinical translation, we developed a Fluorescence Activated Cell Sorting (FACS)‐based technique to rapidly purify transduced progenitors that homogeneously express a desired specific VEGF level from heterogeneous...

Université de Fribourg

Transcutaneous aortic valve implantation using the carotid artery access: Feasibility and clinical outcomes

Kallinikou, Zacharenia ; Berger, Alexandre ; Ruchat, Patrick ; Khatchatourov, Gregory ; Fleisch, Isabelle ; Korkodelovic, Branislav ; Henchoz, Emmanuel ; Marti, René-Andréas ; Cook, Stéphane ; Togni, Mario ; Goy, Jean-Jacques

In: Archives of Cardiovascular Diseases, 2017, vol. 110, no. 6, p. 389–394

Background: Transcarotid access is an alternative route for transcutaneous aortic valve implantation (TAVI) in patients with impossible transfemoral access.Aims: We evaluated the safety, effectiveness and early and late clinical outcomes of CoreValve® implantation via the common carotid artery.Methods: Eighteen patients (10 men, 8 women; mean age 84 ± 5 years) at high surgical risk (mean...

Consortium of Swiss Academic Libraries

Optical coherence tomography findings in renal denervation

Cook, Stéphane ; Goy, Jean-Jacques ; Togni, Mario

In: European Heart Journal, 2012, vol. 33, no. 23, p. 2992-2992

Université de Fribourg

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Jain, Manish ; Zellweger, Matthieu ; Wagnières, Georges ; Bergh, Hubert van den ; Cook, Stéphane ; Giraud, Marie-Noëlle

In: Cardiovascular Therapeutics, 2017, vol. 35, no. 2, p. -

Acute coronary syndrome is a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerable atherosclerotic plaque with secondary platelet activation and thrombus formation, which leads to partial or complete luminal obstruction...