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    Université de Fribourg

    Identification of genes differentially expressed upon cocaine treatment and of new rat semaphorins

    Brenz Verca-Kouznetsova, Maria ; Dreyer, Jean-Luc (Dir.)

    Thèse de doctorat : Université de Fribourg : 2000 ; no 1329.

    At the behavioral level drug addiction is defined as compulsion to take a drug with loss of control over apparently voluntary acts of drug seeking and drug taking. At the neuronal level drugs elicit two types of responses: neuronal adaptations, i.e. homeostatic responses to excessive stimulation, and synaptic plasticity. At the molecular level both processes are paralleled by changes in gene...