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Università della Svizzera italiana

Abandon ship? : party brands and politicians’ responses to a political scandal

Daniele, Gianmarco ; Galletta, Sergio ; Geys, Benny

In this article, we study politicians’ – rather than voters’ – responses to the main political scandal in Italian recent history (Tangentopoli), and overcome endogeneity concerns by analysing the local implications of this national corruption scandal. We find that local politicians withdraw support for incumbents in parties hit by Tangentopoli – inducing increased political...

Consortium of Swiss Academic Libraries

An abstraction refinement approach combining precise and approximated techniques

Sharygina, Natasha ; Tonetta, Stefano ; Tsitovich, Aliaksei

In: International Journal on Software Tools for Technology Transfer, 2012, vol. 14, no. 1, p. 1-14

Università della Svizzera italiana

Accounting for WTP/WTA discrepancy in discrete choice models : discussion of policy implications based on two freight transport stated choice experiments

Masiero, Lorenzo ; Maggi, Rico

A key input in cost-benefit analysis is represented by the marginal rate of substitution which expresses the willingness to pay, or its counterpart willingness to accept, for both market and non-market goods. The consistent discrepancy between these two measures observed in the literature suggests the need to estimate reference dependent models able to capturing loss aversion by...

Università della Svizzera italiana

Accurate short-term yield curve forecasting using functional gradient descent

Audrino, Francesco ; Trojani, Fabio

In: Journal of financial econometrics, 2007, vol. 5, no. 4, p. 591–623

We propose a multivariate nonparametric technique for generating reliable shortterm historical yield curve scenarios and confidence intervals. The approach is based on a Functional Gradient Descent (FGD) estimation of the conditional mean vector and covariance matrix of a multivariate interest rate series. It is computationally feasible in large dimensions and it can account for non- linearities...

Università della Svizzera italiana

ACKR3 expression on diffuse large B cell lymphoma is required for tumor spreading and tissue infiltration

Puddinu, Viola ; Casella, Sabrina ; Radice, Egle ; Thelen, Sylvia ; Dirnhofer, Stefan ; Bertoni, Francesco ; Thelen, Marcus

In: Oncotarget, 2017, vol. 8, no. 49, p. 85068-85084

Diffuse large B cell lymphoma (DLBCL) is the most frequent lymphoma accounting for more than the 30% of the cases. Involvement of extranodal sites, such as bone marrow and central nervous system, is associated with poor prognosis. A contribution of the chemokine system in these processes is assumed as it is known as a critical regulator of the metastatic process in cancer. The atypical...

Università della Svizzera italiana

Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses

Tousa, Sofia ; Semitekolou, Maria ; Morianos, Ioannis ; Banos, Aggelos ; Trochoutsou, Aikaterini I. ; Brodie, Tess M. ; Poulos, Nikolaos ; Samitas, Konstantinos ; Kapasa, Maria ; Konstantopoulos, Dimitris ; Paraskevopoulos, Giannis ; Gaga, Mina ; Hawrylowicz, Catherine M. ; Sallusto, Federica ; Xanthou, Georgina

In: Proceedings of the national academy of sciences of the United States of America, 2017, vol. 114, no. 14, p. E2891-E2900

Type 1 regulatory T (Tr1) cells play a pivotal role in restraining human T-cell responses toward environmental allergens and protecting against allergic diseases. Still, the precise molecular cues that underlie their transcriptional and functional specification remain elusive. Here, we show that the cytokine activin-A instructs the generation of CD4+ T cells that express the...

Consortium of Swiss Academic Libraries

Actualising Bergson's lesson: a post-post-modernist perspective

Colombo, Gianluca

In: Journal of Management & Governance, 2009, vol. 13, no. 3, p. 261-267