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    Université de Fribourg

    The C. elegans Hox gene ceh-13 regulates cell migration and fusion in a non-colinear way. Implications for the early evolution of Hox clusters

    Tihanyi, Borbála ; Vellai, Tibor ; Regős, Ágnes ; Ari, Eszter ; Müller, Fritz ; Takács-Vellai, Krisztina

    In: BMC Developmental Biology, 2010, vol. 10, no. 78, p. 78

    Background: Hox genes play a central role in axial patterning during animal development. They are clustered in the genome and specify cell fate in sequential domains along the anteroposterior (A-P) body axis in a conserved order that is co-linear with their relative genomic position. In the soil worm Caenorhabditis elegans, this striking rule of co-linearity is broken by the anterior Hox gene...