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Dietary potassium and the renal control of salt balance and blood pressure

Penton, David

In: Pflügers Archiv : European Journal of Physiology, ///-

Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics

McKinnon, Brett D. ; Kocbek, Vida ; Nirgianakis, Kostantinos ; Bersinger, Nick A. ; Mueller, Michael D.

In: Human Reproduction Update, 2016, vol. 22, no. 3, p. 382-403

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels

Rougier, Jean-Sebastien ; Albesa, Maxime ; Syam, Ninda ; Halet, Guillaume ; Abriel, Hugues ; Viard, Patricia

In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 9, p. 1919-1929

ENaC activity in collecting ducts modulates NCC in cirrhotic mice

Mordasini, David ; Loffing-Cueni, Dominique ; Loffing, Johannes ; Beatrice, Rohrbach ; Maillard, Marc ; Hummler, Edith ; Burnier, Michel ; Escher, Geneviève ; Vogt, Bruno

In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 12, p. 2529-2539

The lung communication network

Losa, Davide ; Chanson, Marc

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 15, p. 2793-2808

Cathepsin B increases ENaC activity leading to hypertension early in nephrotic syndrome

Larionov, Alexey ; Dahlke, Eileen ; Kunke, Madlen ; Rodriguez, Luis Zanon ; Schiessl, Ina M. ; Magnin, Jean‐Luc ; Kern, Ursula ; Alli, Abdel A. ; Mollet, Geraldine ; Schilling, Oliver ; Castrop, Hayo ; Theilig, Franziska

In: Journal of Cellular and Molecular Medicine, 2019, vol. 23, no. 10, p. 6543–6553

The NPHS2 gene, encoding the slit diaphragm protein podocin, accounts for genetic and sporadic forms of nephrotic syndrome (NS). Patients with NS often present symptoms of volume retention, such as oedema formation or hypertension. The primary dysregulation in sodium handling involves an inappropriate activation of the epithelial sodium channel, ENaC. Plasma proteases in a...

Physiological and Molecular Responses to Altered Sodium Intake in Rat Pregnancy

Eisele, Nicole ; Klossner, Rahel ; Escher, Geneviève ; Rudloff, Stefan ; Larionov, Alexey ; Theilig, Franziska ; Mohaupt, Markus G. ; Mistry, Hiten D. ; Gennari‐Moser, Carine

In: Journal of the American Heart Association, 2018, p. -

In pregnancy, a high plasma volume maintains uteroplacental perfusion and prevents placental ischemia, a condition linked to elevated maternal blood pressure (BP). Reducing BP by increasing Na+ intake via plasma volume expansion appears contra‐ intuitive. We hypothesize that an appropriate Na+ intake in pregnancy reduces maternal BP and adapts the renin‐angiotensin system in a...

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding

Scheib, Holger ; McLay, Iain ; Guex, Nicolas ; Clare, Jeff ; Blaney, Frank ; Dale, Tim ; Tate, Simon ; Robertson, Graeme

In: Journal of Molecular Modeling, 2006, vol. 12, no. 6, p. 813-822

Replication of segment-specific and intercalated cells in the mouse renal collecting system

Wehrli, Philipp ; Loffing-Cueni, Dominique ; Kaissling, Brigitte ; Loffing, Johannes

In: Histochemistry and Cell Biology, 2007, vol. 127, no. 4, p. 389-398

Dual effect of temperature on the human epithelial Na+ channel

Chraïbi, Ahmed ; Horisberger, Jean-Daniel

In: Pflügers Archiv, 2003, vol. 447, no. 3, p. 316-320