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Université de Fribourg

Cenozoic evolution of the steppe-desert biome in Central Asia

Barbolini, N. ; Woutersen, A. ; Dupont-Nivet, G. ; Silvestro, Daniele ; Tardif, D. ; Coster, P. M. C. ; Meijer, N. ; Chang, C. ; Zhang, H.-X. ; Licht, A. ; Rydin, C. ; Koutsodendris, A. ; Han, F. ; Rohrmann, A. ; Liu, X.-J. ; Zhang, Y. ; Donnadieu, Y. ; Fluteau, F. ; Ladant, J.-B. ; Le Hir, G. ; Hoorn, C.

In: Science Advances, 2020, vol. 6, no. 41, p. eabb8227

The origins and development of the arid and highly seasonal steppe-desert biome in Central Asia, the largest of its kind in the world, remain largely unconstrained by existing records. It is unclear how Cenozoic climatic, geological, and biological forces, acting at diverse spatial and temporal scales, shaped Central Asian ecosystems through time. Our synthesis shows that the Central Asian...

Université de Fribourg

Superconductivity-induced transverse plasma mode and phonon anomaly in the $c$-axis response of the bilayer compound ${\mathrm{RbCa}}_{2}{\mathrm{Fe}}_{4}{\mathrm{As}}_{4}{\mathrm{F}}_{2}$

Xu, Bing ; Munzar, Dominik ; Dubroka, Adam ; Sheveleva, Evgeniia ; Lyzwa, Fryderyk ; Maršík, Premysl ; Wang, C. N. ; Wang, Z. C. ; Cao, G. H. ; Bernhard, Christian

In: Physical Review B, 2020, vol. 101, no. 21, p. 214512

We studied the infrared response of polycrystalline samples of the iron arsenide superconductor (Rb,Cs)Ca2Fe4As4F2 (Rb,Cs-12442), which has a bilayer structure similar to the high-Tc cuprates YBa2Cu3O7 (YBCO) and Bi2Sr2CaCu2O8. The c-axis reflectivity spectra Rc have been derived from the reflectivity spectra of the polycrystalline samples Rpoly and the in-plane spectrum of a corresponding...

Université de Fribourg

Computational network biology: Data, models, and applications

Liu, Chuang ; Ma, Yifang ; Zhao, Jing ; Nussinov, Ruth ; Zhang, Yi-Cheng ; Cheng, Feixiong ; Zhang, Zi-Ke

In: Physics Reports, 2020, vol. 846, p. 1–66

Biological entities are involved in intricate and complex interactions, in which uncovering the biological information from the network concepts are of great significance. Benefiting from the advances of network science and high-throughput biomedical technologies, studying the biological systems from network biology has attracted much attention in recent years, and networks have long been...

Université de Fribourg

Predicting financial extremes based on weighted visual graph of major stock indices

Chen, Dong-Rui ; Liu, Chuang ; Zhang, Yi-Cheng ; Zhang, Zi-Ke

In: Complexity, 2019, vol. 2019, p. 1–17

Understanding and predicting extreme turning points in the financial market, such as financial bubbles and crashes, has attracted much attention in recent years. Experimental observations of the superexponential increase of prices before crashes indicate the predictability of financial extremes. In this study, we aim to forecast extreme events in the stock market using 19-year time-series...

Université de Fribourg

Structural insights into the EGO-TC–mediated membrane tethering of the TORC1-regulatory Rag GTPases

Zhang, Tianlong ; Péli-Gulli, Marie-Pierre ; Zhang, Zhen ; Tang, Xin ; Ye, Jie ; Virgilio, Claudio De ; Ding, Jianping

In: Science Advances, 2019, vol. 5, no. 9, p. eaax8164

The Rag/Gtr GTPases serve as a central module in the nutrient-sensing signaling network upstream of TORC1. In yeast, the anchoring of Gtr1-Gtr2 to membranes depends on the Ego1-Ego2-Ego3 ternary complex (EGO-TC), resulting in an EGO- TC-Gtr1-Gtr2 complex (EGOC). EGO-TC and human Ragulator share no obvious sequence similarities and also differ in their composition with respect to the number of ...

Université de Fribourg

Revealing ‘plasmaron’ feature in DySb by optical spectroscopy study

Ban, W J ; Wu, D S ; Xu, Bing ; Luo, J L ; Xiao, Hong

In: Journal of Physics: Condensed Matter, 2019, vol. 31, no. 40, p. 405701

We report magnetic susceptibility, resistivity and optical spectroscopy study on single crystal sample DySb. It exhibits extremely large magnetoresistance (XMR), and a magnetic phase transition from paramagnetic (PM) to antiferromagnetic (AFM) state at about 10 K. A 'screened' plasma edge at about 4000 cm−1 is revealed by optical measurement, which suggests that the material has a low...

Université de Fribourg

Measurement of ultra-trace level of intact oxytocin in plasma using SALLE combined with nano-LC–MS

Liu, Dan ; Han, Xiaoli ; Liu, Xinxin ; Cheng, Mengchun ; He, Meixi ; Rainer, Gregor ; Gao, Huiyuan ; Zhang, Xiaozhe

In: Journal of Pharmaceutical and Biomedical Analysis, 2019, vol. 173, p. 62–67

Measurement of peptides such as oxytocin in plasma is a critical challenge in clinical research because of their extreme low concentrations as well as the tremendous interferencing substances co-presented in plasma. In this study, we developed an efficient salt-out assisted liquid-liquid extraction (SALLE) to treat plasma, and then analyzed the samples using nano-LC–MS to quantify intact...

Université de Fribourg

A novel Ca2+-binding protein that can rapidly transduce auxin responses during root growth

Hazak, Ora ; Mamon, Elad ; Lavy, Meirav ; Sternberg, Hasana ; Behera, Smrutisanjita ; Schmitz-Thom, Ina ; Bloch, Daria ; Dementiev, Olga ; Gutman, Itay ; Danziger, Tomer ; Schwarz, Netanel ; Abuzeineh, Anas ; Mockaitis, Keithanne ; Estelle, Mark ; Hirsch, Joel A. ; Kudla, Jörg ; Yalovsky, Shaul

In: PLOS Biology, 2019, vol. 17, no. 7, p. e3000085

Signaling cross talks between auxin, a regulator of plant development, and Ca2+, a universal second messenger, have been proposed to modulate developmental plasticity in plants. However, the underlying molecular mechanisms are largely unknown. Here, we report that in Arabidopsis roots, auxin elicits specific Ca2+ signaling patterns that spatially coincide with the expression pattern of...

Université de Fribourg

ABCG36/PEN3/PDR8 Is an Exporter of the Auxin Precursor, Indole-3-Butyric Acid, and Involved in Auxin-Controlled Development

Aryal, Bibek ; Huynh, John ; Schneuwly, Jerôme ; Siffert, Alexandra ; Liu, Jie ; Alejandro, Santiago ; Ludwig-Müller, Jutta ; Martinoia, Enrico ; Geisler, Markus

In: Frontiers in Plant Science, 2019, vol. 10, p. -

The PDR-type ABCG transporter, ABCG36/PDR8/PEN3, is thought to be implicated in the export of a few structurally unrelated substrates, including the auxin precursor, indole-3-butyric acid (IBA), although a clear-cut proof of transport is lacking. An outward facing, lateral root (LR) location for ABCG36 fuelled speculations that it might secrete IBA into the rhizosphere. Here, we provide...

Université de Fribourg

Do invasive alien plants differ from non-invasives in dominance and nitrogen uptake in response to variation of abiotic and biotic environments under global anthropogenic change?

Liu, Yuan-Yuan ; Sun, Yan ; Müller-Schärer, Heinz ; Yan, Rong ; Zhou, Zhi-Xiang ; Wang, Yong-Jian ; Yu, Fei-Hai

In: Science of The Total Environment, 2019, vol. 672, p. 634–642

Plant invasion is the outcome of complicated interactions of both biotic and abiotic environments (i.e. eutrophication and human-induced propagules) under global anthropogenic change. Here, we want to know why some alien clonal plant species become invasive and others do not in the introduced range with variations of both abiotic and biotic environments under global anthropogenic change.We...