In: Advanced Science, 2021, p. 2100995
As wearable technologies redefine the way people exchange information, receive entertainment, and monitor health, the development of sustainable power sources that capture energy from the user's everyday activities garners increasing interest. Electric fishes, such as the electric eel and the torpedo ray, provide inspiration for such a power source with their ability to generate massive...
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In: Nano Research, 2020, vol. 13, no. 10, p. 2847–2856
Nanoparticle (NP) colloidal stability plays a crucial role in biomedical application not only for human and environmental safety but also for NP efficiency and functionality. NP agglomeration is considered as a possible process in monodispersed NP colloidal solutions, which drastically affects colloidal stability. This process is triggered by changes in the physicochemical properties of the...
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In: Nature Nanotechnology, 2020, p. 1–10
In plants, pathogen attack can induce an immune response known as systemic acquired resistance that protects against a broad spectrum of pathogens. In the search for safer agrochemicals, silica nanoparticles (SiO2 NPs; food additive E551) have recently been proposed as a new tool. However, initial results are controversial, and the molecular mechanisms of SiO2 NP-induced disease resistance...
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In: Angewandte Chemie International Edition, 2020, vol. 60, no. 2, p. 904-909
Some marine plankton called dinoflagellates emit light in response to the movement of surrounding water, resulting in a phenomenon called milky seas or sea sparkle. The underlying concept, a shear-stress induced permeabilisation of biocatalytic reaction compartments, is transferred to polymer-based nanoreactors. Amphiphilic block copolymers that carry nucleobases in their hydrophobic block...
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In: Cells, 2020, vol. 9, no. 9, p. 2099
Silica nanoparticles (NPs) are widely used in various industrial and biomedical applications. Little is known about the cellular uptake of co-exposed silica particles, as can be expected in our daily life. In addition, an inflamed microenvironment might affect a NP’s uptake and a cell’s physiological response. Herein, prestimulated mouse J774A.1 macrophages with bacterial...
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In: Nature Nanotechnology, 2020, vol. 15, no. 9, p. 729–730
Overcoming the challenges of plastic detection in plants has made it possible to transfer many of the lessons learned from plant–metal nanoparticle interactions to plastic nanoparticles.
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In: Nanoscale, 2020, vol. 12, no. 33, p. 17362–17372
Evaluating nanomaterial uptake and association by cells is relevant for in vitro studies related to safe-by-design approaches, nanomedicine or applications in photothermal therapy. However, standard analytical techniques are time-consuming, involve complex sample preparation or include labelling of the investigated sample system with e.g. fluorescent dyes. Here, we explore lock-in...
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In: Advanced Functional Materials, 2020, p. 2002630
Nanoparticle adsorption to substrates pose a unique challenge to understand uptake mechanisms as it involves the organization of complex cytoskeletal components by cells to perform endocytosis/phagocytosis. In particular, it is not well‐understood from a cell mechanics perspective how the adhesion of particles on substrate will influence the ease of material clearance. By using a particle...
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In: Materials, 2020, vol. 13, no. 9, p. 2018
Magnetosomes are near-perfect intracellular magnetite nanocrystals found in magnetotactic bacteria. Their synthetic imitation, known as superparamagnetic iron oxide nanoparticles (SPIONs), have found applications in a variety of (nano)medicinal fields such as magnetic resonance imaging contrast agents, multimodal imaging and drug carriers. In order to perform these functions in medicine,...
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In: Nanomedicine, 2020, vol. 15, no. 3, p. 259–271
Aim: Design nanostructured lipid carriers (NLC) to facilitate drug delivery to tuberculosis-infected areas, exploiting macrophage mannose receptors and assess their uptake in a 3D human lung model. Materials & methods: NLCs and mannosylated-NLCs were synthetized and characterized. Their uptake and biocompatibility were tested in a 3D human lung model. Results: The formulations have...
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