In: Cerebral Cortex, 2017, vol. 27, no. 6, p. 3217-3230
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In: Journal of Biomolecular NMR, 2015, vol. 62, no. 4, p. 453-471
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In: Human Molecular Genetics, 2018, vol. 27, no. 21, p. 3825-3825
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In: Human Molecular Genetics, 2018, vol. 27, no. 12, p. 2039-2051
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In: Journal of Biomolecular NMR, 2015, vol. 62, no. 1, p. 81-95
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In: Journal of Biomolecular NMR, 2015, vol. 63, no. 1, p. 21-37
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In: Blood, 2020, vol. 135, no. 15, p. 1244–1254
CD49d is a remarkable prognostic biomarker of chronic lymphocytic leukemia (CLL). The cutoff value for the extensively validated 30% of positive CLL cells is able to separate CLL patients into 2 subgroups with different prognoses, but it does not consider the pattern of CD49d expression. In the present study, we analyzed a cohort of 1630 CLL samples and identified the presence of ∼20% of CLL...
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In: Haematologica, 2020, vol. 105, no. 2, p. 448-456
BIRC3 is a recurrently mutated gene in chronic lymphocytic leukemia (CLL) but the functional implications of BIRC3 mutations are largely unexplored. Furthermore, little is known about the prognostic impact of BIRC3 mutations in CLL cohorts homogeneously treated with first-line fludarabine, cyclophosphamide, and rituximab (FCR). By immunoblotting analysis, we showed that the non-canonical...
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In: Autophagy, 2020, p. 1-21
Mitochondria-associated membranes (MAMs) are essential communication subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. We previously demonstrated that, upon macroautophagy/autophagy induction, AMBRA1 is recruited to the BECN1 complex and relocalizes to MAMs, where it regulates autophagy by interacting with raft-like components. ERLIN1 is an endoplasmic reticulum...
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In: International Journal of Molecular Sciences, 2020, vol. 21, no. 10, p. 3691
Mitochondria alterations are a classical feature of muscle immobilization, and autophagy is required for the elimination of deficient mitochondria (mitophagy) and the maintenance of muscle mass. We focused on the regulation of mitochondrial quality control during immobilization and remobilization in rat gastrocnemius (GA) and tibialis anterior (TA) muscles, which have very different atrophy...
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