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Università della Svizzera italiana

Fibrin sealants and axillary lymphatic morbidity : a systematic review and meta-analysis of 23 clinical randomized trials

Gasparri, Maria Luisa ; Kuehn, Thorsten ; Ruscito, Ilary ; Zuber, Veronica ; Di Micco, Rosa ; Galiano, Ilaria ; Navarro Quinones, Siobana C. ; Santurro, Letizia ; Di Vittorio, Francesca ; Meani, Francesco ; Bassi, Valerio ; Ditsch, Nina ; Mueller, Michael D. ; Bellati, Filippo ; Caserta, Donatella ; Papadia, Andrea ; Gentilini, Oreste D.

In: Cancers, 2021, vol. 13, no. 9, p. 15

Axillary dissection is a highly mobile procedure with severe lymphatic consequences. The off-label application of fibrin sealants in the axilla, with the sole aim to eliminate dead space and to provoke sealing of the disrupted lymphatic vessels at the end of axillary dissection, is an experimental procedure to reduce lymphatic morbidity. The aim of our systematic review and meta-analysis is to ...

Università della Svizzera italiana

Epithelial-mesenchymal transition in cancer metastasis through the lymphatic syste

Karlsson, Mikael C. ; Gonzalez, Santiago F. ; Welin, Josefin ; Fuxe, Jonas

In: Molecular oncology, 2017, vol. 11, p. 781–791

It was already in the 18th century when the French surgeon LeDran first noted that breast cancer patients with spread of tumor cells to their axillary lymph nodes had a drastically worse prognosis than patients without spread (LeDran et al., ). Since then, metastatic spread of cancer cells to regional lymph nodes has been established as the most important prognostic factor in many types of...

Università della Svizzera italiana

Macrophage death following influenza vaccination initiates the inflammatory response that promotes dendritic cell function in the draining lymph node

Chatziandreou, Nikolaos ; Farsakoglu, Yagmur ; Palomino-Segura, Miguel ; D’Antuono, Rocco ; Pizzagalli, Diego Ulisse ; Sallusto, Federica ; Lukacs-Kornek, Veronika ; Uguccioni, Mariagrazia ; Corti, Davide ; Turley, Shannon J. ; Lanzavecchia, Antonio ; Carroll, Michael C. ; Gonzalez, Santiago F.

In: Cell reports, 2017, vol. 18, no. 10, p. 2427-2440

The mechanism by which inflammation influences the adaptive response to vaccines is not fully understood. Here, we examine the role of lymph node macrophages (LNMs) in the induction of the cytokine storm triggered by inactivated influenza virus vaccine. Following vaccination, LNMs undergo inflammasome-independent necrosis-like death that is reliant on MyD88 and Toll-like receptor 7 (TLR7)...

Consortium of Swiss Academic Libraries

Mark M. Wilde: Quantum information theory

Renes, Joseph

In: Quantum Information Processing, 2014, vol. 13, no. 2, p. 587-590