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Université de Fribourg

Divergent solutions to visual problem solving across mammalian species

Mustafar, Faiz ; Harvey, Michael A. ; Khani, Abbas ; Arató, József ; Rainer, Gregor

In: eNeuro, 2018, vol. 5, no. 4, p. -

Our understanding of the neurobiological underpinnings of learning and behavior relies on the use of invasive techniques, which necessitate the use of animal models. However, when different species learn the same task, to what degree are they actually producing the same behavior and engaging homologous neural circuitry? This question has received virtually no recent attention, even as the...

Université de Fribourg

Distinct frequency specialization for detecting dark transients in humans and tree shrews

Khani, Abbas ; Mustafar, Faiz ; Rainer, Gregor

In: Cell Reports, 2018, vol. 23, no. 8, p. 2405–2415

Despite well-known privileged perception of dark over light stimuli, it is unknown to what extent this dark dominance is maintained when visual transients occur in rapid succession, for example, during perception of moving stimuli. Here, we address this question using dark and light transients presented at different flicker frequencies. Although both human participants and tree shrews...

Université de Fribourg

Stress impacts the regulation neuropeptides in the rat hippocampus and prefrontal cortex

Li, Wenxue ; Papilloud, Aurelie ; Lozano-Montes, Laura ; Zhao, Nan ; Ye, Xueting ; Zhang, Xiaozhe ; Sandi, Carmen ; Rainer, Gregor

In: PROTEOMICS, 2018, vol. 18, no. 7, p. 1700408

Adverse life experiences increase the lifetime risk to several stress‐related psychopathologies, such as anxiety or depressive‐like symptoms following stress in adulthood. However, the neurochemical modulations triggered by stress have not been fully characterized. Neuropeptides play an important role as signaling molecules that contribute to physiological regulation and have been linked...