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Université de Fribourg

Silica nanoparticles enhance disease resistance in Arabidopsis plants

El-Shetehy, Mohamed ; Moradi, Aboubakr ; Maceroni, Mattia ; Reinhardt, Didier ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara ; Mauch, Felix ; Schwab, Fabienne

In: Nature Nanotechnology, 2020, p. 1–10

In plants, pathogen attack can induce an immune response known as systemic acquired resistance that protects against a broad spectrum of pathogens. In the search for safer agrochemicals, silica nanoparticles (SiO2 NPs; food additive E551) have recently been proposed as a new tool. However, initial results are controversial, and the molecular mechanisms of SiO2 NP-induced disease resistance...

Université de Fribourg

Granzyme B attenuates bacterial virulence by targeting secreted factors

López León, Diego ; Matthey, Patricia ; Fellay, Isabelle ; Blanchard, Marianne ; Martinvalet, Denis ; Mantel, Pierre-Yves ; Filgueira, Luis ; Walch, Michael

In: iScience, 2020, vol. 23, no. 3, p. 100932

Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show that granzyme B degrades multiple secreted virulence mediators from Listeria monocytogenes,...

Université de Fribourg

Intra and extracellular journey of the phytohormone salicylic acid

Maruri-López, Israel ; Aviles-Baltazar, Norma Yaniri ; Buchala, Antony J. ; Serrano, Mario

In: Frontiers in Plant Science, 2019, vol. 10, p. -

Salicylic acid (SA) is a plant hormone that has been described to play an essential role in the activation and regulation of multiple responses to biotic and to abiotic stresses. In particular, during plant-microbe interactions, as part of the defense mechanisms, SA is initially accumulated at the local infected tissue and then spread all over the plant to induce systemic acquired resistance...

Université de Fribourg

Beneficial services of arbuscular mycorrhizal fungi – from ecology to application

Chen, Min ; Arato, Miguel ; Borghi, Lorenzo ; Nouri, Eva ; Reinhardt, Didier

In: Frontiers in Plant Science, 2018, vol. 9, p. -

Arbuscular mycorrhiza (AM) is the most common symbiotic association of plants with microbes. AM fungi occur in the majority of natural habitats and they provide a range of important ecological services, in particular by improving plant nutrition, stress resistance and tolerance, as well as soil structure and fertility. AM fungi interact with most crop plants including cereals, vegetables, and...

Consortium of Swiss Academic Libraries

The CDK inhibitors in cancer research and therapy

Cicenas, Jonas ; Valius, Mindaugas

In: Journal of Cancer Research and Clinical Oncology, 2011, vol. 137, no. 10, p. 1409-1418