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Università della Svizzera italiana

PPARgamma in dendritic cells and T cells drives pathogenic type-2 effector responses in lung inflammation

Nobs, Samuel Philip ; Natali, Sara ; Pohlmeier, Lea ; Okreglicka, Katarzyna ; Schneider, Christoph ; Kurrer, Michael ; Sallusto, Federica ; Kopf, Manfred

In: Journal of experimental medicine, 2017, vol. 214, no. 10, p. 3015-3035

Type-2 immune responses are well-established drivers of chronic inflammatory diseases, such as asthma, and represent a large burden on public health systems. The transcription factor PPARγ is known to promote M2-macrophage and alveolar macrophage development. Here, we report that PPARγ plays a key role in both T cells and dendritic cells (DCs) for development of type-2 immune responses. It...

Haute école de gestion de Genève

The meaning of Architecture in Information Architecture : analysis and reflection

Fuss, Megan ; Schneider, René (Dir.)

Mémoire de master : Haute école de gestion de Genève, 2018 ; MASID 63.

There are various ways of identifying ‘Architecture’. It takes different shapes depending on the circumstances and the field of study, forming distinct disciplines. Furthermore, they all follow their own set of defined characteristics and principles that are reflective of their good practices and of how they are characterized. This paper converges both Information Architecture and...

Université de Fribourg

Interactions of "Sarracenia purpurea" and its inquilines : comparing Europe and North America

Zander, Axel ; Bersier, Louis-Félix (Dir.)

Thèse de doctorat : Université de Fribourg, 2016 ; no. 1984.

Sarracenia purpurea is a carnivorous pitcher plant from North America and a model system for aquatic communities. After the pitchers fill up with rainwater, a food web forms in these detritus-fueled ecosystems ranging from bacteria to insect larvae, including the top predator Wyeomyia smithii. Two weeks after opening this food webs consists only of a handful of small and fast dispersing species...

Université de Fribourg

Phase segregation in supramolecular polymers based on telechelics synthesized via multicomponent reactions

Sehlinger, Ansgar ; Bartnick, Nikolai ; Gunkel, Ilja ; Meier, Michael A. R. ; Montero de Espinosa, Lucas

In: Macromolecular Chemistry and Physics, 2017, vol. 218, no. 22, p. 1700302

The properties of supramolecular polymers in the solid state are strongly dependent on the binding strength of the supramolecular motifs used; however, It has been previously shown that the nanostructure of supramolecular polymers plays an equally important role. Supramolecular polymers are commonly synthesized via end-group functionalization of low-glass transition telechelics with...