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Staphylococcal biofilm formation on the surface of three different calcium phosphate bone grafts: a qualitative and quantitative in vivo analysis

Furustrand Tafin, Ulrika ; Betrisey, Bertrand ; Bohner, Marc ; Ilchmann, Thomas ; Trampuz, Andrej ; Clauss, Martin

In: Journal of Materials Science: Materials in Medicine, 2015, vol. 26, no. 3, p. 1-8

Comparison of phenotypic methods for the detection of penicillinase in Staphylococcus aureus and proposal of a practical diagnostic approach

Hombach, Michael ; Weissert, Christoph ; Senn, Maria Magdalena ; Zbinden, Reinhard

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 4, p. 1089-1093

Fully automated disc diffusion for rapid antibiotic susceptibility test results: a proof-of-principle study

Hombach, Michael

In: Journal of Antimicrobial Chemotherapy, ///-

Rapid detection of ESBL, carbapenemases, MRSA and other important resistance phenotypes within 6-8 h by automated disc diffusion antibiotic susceptibility testing

Hombach, Michael

In: Journal of Antimicrobial Chemotherapy, ///-

Comparative Genomics of Community-Associated Methicillin-Resistant Staphylococcus aureus Shows the Emergence of Clone ST8-USA300 in Geneva, Switzerland

Von Dach, Elodie ; Diene, Seydina M. ; Fankhauser, Carolina ; Schrenzel, Jacques ; Harbarth, Stephan ; François, Patrice

In: The Journal of Infectious Diseases, 2016, vol. 213, no. 9, p. 1370-1379

Prospective, cross-sectional study on MSSA and MRSA colonisation in hospitalised children

Johnson, Kristen ; Frei, Reno ; Heininger, Ulrich

In: European Journal of Pediatrics, 2015, vol. 174, no. 9, p. 1255-1262

Emergence of colistin-resistant Gram-negative Enterobacterales in the gut of patients receiving oral colistin and neomycin decontamination

Lastours, Victoire de ; Poirel, Laurent ; Huttner, Benedikt ; Harbarth, Stephan ; Denamur, Erick ; Nordmann, Patrice

In: Journal of Infection, 2020, vol. 80, no. 5, p. 578–606

Dimercaptosuccinic acid in combination with carbapenems against isogenic strains of Escherichia coli producing or not producing a metallo-β-lactamase in vitro and in murine peritonitis

Cheminet, G. ; de Lastours, V. ; Poirel, Laurent ; Chau, F. ; Peoc’h, K. ; Massias, L. ; Fantin, B. ; Nordmann, Patrice

In: Journal of Antimicrobial Chemotherapy, 2020, vol. 75, no. 12, p. 3593–3600

Background: Carbapenemase-producing Enterobacterales represent a major therapeutic challenge. MBLs, requiring zinc at their catalytic site, could be inhibited by meso-dimercaptosuccinic acid (DMSA), a heavy metal chelator already widely used for treating lead intoxication.Objectives: To evaluate the activity of carbapenems alone or combined with DMSA against MBL-producing Escherichia coli in...

NGS-based S. aureus typing and outbreak analysis in clinical microbiology laboratories : Lessons learned from a Swiss-wide proficiency test

Dylus, David ; Pillonel, Trestan ; Opota, Onya ; Wüthrich, Daniel ; Seth-Smith, Helena M. B. ; Egli, Adrian ; Leo, Stefano ; Lazarevic, Vladimir ; Schrenzel, Jacques ; Laurent, Sacha ; Bertelli, Claire ; Blanc, Dominique S. ; Neuenschwander, Stefan ; Ramette, Alban ; Falquet, Laurent ; Imkamp, Frank ; Keller, Peter M. ; Kahles, Andre ; Oberhaensli, Simone ; Barbié, Valérie ; Dessimoz, Christophe ; Greub, Gilbert ; Lebrand, Aitana

In: Frontiers in Microbiology, 2020, vol. 11, p. 591093

Whole genome sequencing (WGS) enables high resolution typing of bacteria up to the single nucleotide polymorphism (SNP) level. WGS is used in clinical microbiology laboratories for infection control, molecular surveillance and outbreak analyses. Given the large palette of WGS reagents and bioinformatics tools, the Swiss clinical bacteriology community decided to conduct a ring trial (RT) to...

High colonization rate and heterogeneity of ESBL- and carbapenemase-producing enterobacteriaceae isolated from gull feces in Lisbon, Portugal

Aires-de-Sousa, Marta ; Fournier, Claudine ; Lopes, Elizeth ; Lencastre, Hermínia de ; Nordmann, Patrice ; Poirel, Laurent

In: Microorganisms, 2020, vol. 8, no. 10, p. 1487

In order to evaluate whether seagulls living on the Lisbon coastline, Portugal, might be colonized and consequently represent potential spreaders of multidrug-resistant bacteria, a total of 88 gull fecal samples were screened for detection of extended- spectrum β-lactamase (ESBL)- or carbapenemase-producing Enterobacteriaceae for methicillin-resistant Staphylococcus aureus (MRSA) and for...