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Università della Svizzera italiana

Isonitrile-based multicomponent synthesis of β-amino boronic acids as β-lactamase inhibitors

Bassini, Emanuele ; Gazzotti, Stefano ; Sannio, Filomena ; Lo Presti, Leonardo ; Sgrignani, Jacopo ; Docquier, Jean-Denis ; Grazioso, Giovanni ; Silvani, Alessandra

In: Antibiotics, 2020, vol. 9, no. 5, p. 21 p

The application of various isonitrile-based multicomponent reactions to protected (2-oxoethyl)boronic acid (as the carbonyl component) is described. The Ugi reaction, both in the four components and in the four centers–three components versions, and the van Leusen reaction, proved effective at providing small libraries of MIDA-protected β-aminoboronic acids. The corresponding free...

Université de Fribourg

Nonequilibrium solid-solid phase transition in a lattice of liquid jets

Croccolo, Fabrizio ; Castellini, Stefano ; Scheffold, Frank ; Vailati, Alberto

In: Physical Review E, 2018, vol. 98, no. 6, p. 063104

Solid-solid phase transitions are commonly encountered at the atomic scale in alloys and in superatomic mesoscopic systems of colloidal particles. Here we investigate a solid-solid phase transition occurring at the macroscopic scale between lattices of liquid jets with different symmetries generated by convection in a horizontal layer of a binary liquid mixture. In the absence of a shear...

Consortium of Swiss Academic Libraries

Heterodyne Doppler global velocimetry

Meier, Alexander ; Roesgen, Thomas

In: Experiments in Fluids, 2009, vol. 47, no. 4-5, p. 665-672

Consortium of Swiss Academic Libraries

Imaging laser Doppler velocimetry

Meier, Alexander ; Roesgen, Thomas

In: Experiments in Fluids, 2012, vol. 52, no. 4, p. 1017-1026

Université de Fribourg

Differential dynamic microscopy microrheology of soft materials: A tracking-free determination of the frequency-dependent loss and storage moduli

Edera, Paolo ; Bergamini, Davide ; Trappe, Véronique ; Giavazzi, Fabio ; Cerbino, Roberto

In: Physical Review Materials, 2017, vol. 1, no. 7, p. 073804

Particle-tracking microrheology (PT-μr) exploits the thermal motion of embedded particles to probe the local mechanical properties of soft materials. Despite its appealing conceptual simplicity, PT-μr requires calibration procedures and operating assumptions that constitute a practical barrier to its wider application. Here we demonstrate differential dynamic microscopy microrheology...