In: Biomolecular NMR Assignments, 2015, vol. 9, no. 1, p. 7-14
|
In: Physical Chemistry Chemical Physics, 2015, vol. 17, no. 24, p. 15589–15597
Alpha-synuclein (AS) is a synaptic protein that is directly involved in Parkinson's disease due to its tendency to form protein aggregates. Since AS aggregation can be dependent on the interactions between the protein and the cell plasma membrane, elucidating the membrane binding properties of AS is of crucial importance to establish the molecular basis of AS aggregation into toxic fibrils....
|
In: International journal of molecular sciences, 2018, vol. 19, no. 2, p. 571
Alzheimer’s disease is the most fatal neurodegenerative disorder characterized by the aggregation and deposition of Amyloid β (Aβ) oligomers in the brain of patients. Two principal variants of Aβ exist in humans: Aβ1–40 and Aβ1–42. The former is the most abundant in the plaques, while the latter is the most toxic species and forms fibrils more rapidly. Interestingly, fibrils of...
|
In: Applied Physics B, 2014, vol. 117, no. 2, p. 667-672
|
In: Biomolecular NMR Assignments, 2014, vol. 8, no. 2, p. 365-370
|
In: Biomolecular NMR Assignments, 2014, vol. 8, no. 2, p. 349-356
|
In: Biomolecular NMR Assignments, 2014, vol. 8, no. 2, p. 395-404
|
In: Biomaterials, 2019, vol. 190–191, p. 111–120
Although immunotherapy shows great promise for the long-term control of cancer, many tumors still fail to respond to treatment. To improve the outcome, the delivery of immunostimulants to the lymph nodes draining the tumor, where the antitumor immune response is initiated, is key. Efforts to use nanoparticles as carriers for cancer immunotherapy have generally required targeting agents and...
|
In: Scientific Reports, 2019, vol. 9, no. 1, p. 900
As a highly interdisciplinary field, working with nanoparticles in a biomedical context requires a robust understanding of soft matter physics, colloidal behaviors, nano- characterization methods, biology, and bio-nano interactions. When reporting results, it can be easy to overlook simple, seemingly trivial experimental details. In this context, we set out to understand how in vitro...
|
In: Nanoscale, 2018, vol. 10, no. 47, p. 22189–22195
The realization of non-close-packed nanoscale patterns with multiple feature sizes and length scales via colloidal self-assembly is a highly challenging task. We demonstrate here the creation of a variety of tunable particle arrays by harnessing the sequential self-assembly and deposition of two differently sized microgel particles at the fluid–fluid interface. The two-step process is...
|