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Università della Svizzera italiana

Proteome-wide analysis of HIV-specific naive and memory CD4+ T cells in unexposed blood donors

Campion, Suzanne L. ; Brodie, Tess M. ; Fischer, William ; Korber, Bette T. ; Rossetti, Astrea ; Goonetilleke, Nilu ; McMichael, Andrew J. ; Sallusto, Federica

In: Journal of experimental medicine, 2014, vol. 211, no. 7, p. 1273-1280

The preexisting HIV-1–specific T cell repertoire must influence both the immunodominance of T cells after infection and immunogenicity of vaccines. We directly compared two methods for measuring the preexisting CD4+ T cell repertoire in healthy HIV-1–negative volunteers, the HLA-peptide tetramer enrichment and T cell library technique, and show high concordance (r = 0.989). Using the...

Université de Neuchâtel

Etre élève et exprimer une pensée propre: un paradoxe ?

Breux, Stéphanie ; Perret-Clermont, Anne-Nelly

In: Enseignement du français: les apports de la recherche en linguistique. Réflexions en l'honneur de Marie-José Béguelin, 2014, p. 327-340

Université de Neuchâtel

Working memory and semantic involvement in sentence processing: A case of pure progressive amnesia

Fossard, Marion ; Rigalleau, François ; Puel, Michèle ; Nespoulous, Jean-Luc ; Viallard, Gérard ; Démonet, Jean-François ; Cardebat, Dominique

In: Neuropsychologia, 2006, vol. 44, no. 3, p. 335-338

ED, a 83-year-old woman, meets the criteria of pure progressive amnesia, with gradual impairment of episodic and autobiographical memory, sparing of semantic processing and strong working memory (WM) deficit. The dissociation between disturbed WM and spared semantic processing permitted testing the role of WM in processing anaphors like pronouns or repeated names. Results showed a globally normal...

Université de Neuchâtel

Apports de la psycholinguistique

Fossard, Marion ; Macoir, Joël

In: Guide de l'orthophoniste. Savoirs fondamentaux de l'orthophoniste. Savoirs dans le domaine des sciences du langage, 2016, vol. 1, p. 68-75

Université de Neuchâtel

Prise en charge des troubles de la communication consécutifs à un traumatisme crânio-cérébral : une revue systématique

Cordonier, Natacha

In: Aphasie et domaines associés, 2017, vol. 1, p. 46-59

Suite à un traumatisme crânio-cérébral, plusieurs individus présentent des troubles de la communication pouvant affecter la prosodie, le discours et/ou la pragmatique. Ces déficits sont une source importante de handicap, dans la mesure où ils constituent un frein à la réintégration professionnelle et sociale, et ce encore plusieurs années après le traumatisme. Le diagnostic de tels...

Université de Neuchâtel

Toward an Executive Origin for Acquired Phonological Dyslexia: A Case of Specific Deficit of Context-Sensitive Grapheme-to-Phoneme Conversion Rules

Auclair-Ouellet, Noémie ; Fossard, Marion ; St-Pierre Catherine ; Macoir, Joël

In: Behavioural Neurology, 2013, vol. 26, p. 171-173

Phonological dyslexia is a written language disorder characterized by poor reading of nonwords when compared with relatively preserved ability in reading real words. In this study, we report the case of FG, a 74-year-old man with phonological dyslexia. The nature and origin of his reading impairment were assessed using tasks involving activation and explicit manipulation of phonological...

Université de Neuchâtel

Theory of mind and cognitive processes in aging and Alzheimer type dementia: a systematic review

Démonet, Jean-François ; Fossard, Marion ; Sandoz, Mélanie

In: Aging & Mental Health, 2014, vol. 18, no. 7, p. 815-827

Objectives: Theory of mind (ToM) performance in aging and dementia of the Alzheimer type (DAT) has been a growing interest of researchers and recently, theoretical trends in ToM development have led to a focus on determining the cognitive skills involved in ToM performance. The aim of the present review is to answer three main questions: How is ToM assessed in aging and DAT? How does ToM...