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Université de Fribourg

A twist in the ABC : regulation of ABC transporter trafficking and transport by FK506‐binding proteins

Geisler, Markus ; Hegedűs, Tamás

In: FEBS Letters, 2020, vol. 594, no. 23, p. 3986-4000

Post-transcriptional regulation of ATP-binding cassette (ABC) proteins has been so far shown to encompass protein phosphorylation, maturation, and ubiquitination. Yet, recent accumulating evidence implicates FK506-binding proteins (FKBPs), a type of peptidylprolyl cis–trans isomerase (PPIase) proteins, in ABC transporter regulation. In this perspective article, we summarize current knowledge on...

Université de Fribourg

ABCG36/PEN3/PDR8 Is an Exporter of the Auxin Precursor, Indole-3-Butyric Acid, and Involved in Auxin-Controlled Development

Aryal, Bibek ; Huynh, John ; Schneuwly, Jerôme ; Siffert, Alexandra ; Liu, Jie ; Alejandro, Santiago ; Ludwig-Müller, Jutta ; Martinoia, Enrico ; Geisler, Markus

In: Frontiers in Plant Science, 2019, vol. 10, p. -

The PDR-type ABCG transporter, ABCG36/PDR8/PEN3, is thought to be implicated in the export of a few structurally unrelated substrates, including the auxin precursor, indole-3-butyric acid (IBA), although a clear-cut proof of transport is lacking. An outward facing, lateral root (LR) location for ABCG36 fuelled speculations that it might secrete IBA into the rhizosphere. Here, we provide...

Consortium of Swiss Academic Libraries

Cholesterol Transport and Regulation in the Mammary Gland

Ontsouka, Edgar ; Albrecht, Christiane

In: Journal of Mammary Gland Biology and Neoplasia, 2014, vol. 19, no. 1, p. 43-58

Consortium of Swiss Academic Libraries

The bile salt export pump

Stieger, Bruno ; Meier, Yvonne ; Meier, Peter

In: Pflügers Archiv - European Journal of Physiology, 2007, vol. 453, no. 5, p. 611-620