In: Clinical and Translational Imaging, 2021, vol. 9, no. 4, p. 353–360
Background: Physiological focal radiopharmaceutical uptake in the head and uncinate process of the pancreas may be seen on somatostatin receptor-based PET/CT and might lead to false-positive results for neuroendocrine tumours (NETs). We aimed to perform a systematic review and a meta-analysis about the prevalence of this finding. Methods: We performed a comprehensive computer literature search...
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In: European Journal of Applied Physiology, 2015, vol. 115, no. 6, p. 1321-1321
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In: Sleep, 2016, vol. 39, no. 3, p. 589-601
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In: Artificial Life and Robotics, 2015, vol. 20, no. 4, p. 347-352
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In: European Journal of Applied Physiology, 2015, vol. 115, no. 6, p. 1313-1320
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In: Frontiers in Physiology, 2020, vol. 11, p. -
Endogenous circadian rhythms are biological processes generated by an internal body clock. They are self-sustaining, and they govern biochemical and physiological processes. However, circadian rhythms are influenced by many external stimuli to reprogram the phase in response to environmental change. Through their adaptability to environmental changes, they synchronize physiological responses...
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In: Scientific Reports, 2020, vol. 10, no. 1, p. 2752
Organisms possess an endogenous molecular clock which enables them to adapt to environmental rhythms and to synchronize their metabolism and behavior accordingly. Circadian rhythms govern daily oscillations in numerous physiological processes, and the underlying molecular components have been extensively described from fruit flies to mammals. Drosophila larvae have relatively simple nervous...
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In: Theriogenology, 2020, vol. 154, p. 212–222
In rats, birth timing is affected by changes in the light schedule until the middle of the pregnancy period. This phenomenon can be used to control birth timing in the animal industry and/or clinical fields. However, changes in the light schedule until the middle of the pregnancy period can damage the fetus by affecting the development of the major organs. Thus, we compared birth timing in...
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In: Journal of Molecular Biology, 2020, vol. 432, no. 12, p. 3714–3721
The circadian system consists of individual cellular clocks. It organizes and synchronizes biochemical and physiological processes in order to optimally adapt an organism to its environment. This requires that the circadian system is responsive to environmental cues, which contain information about geophysical time (e.g., light), and allows an organism to predict daily recurring events....
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In: eLife, 2019, vol. 8, p. e50925
Circadian oscillations emerge from transcriptional and post-translational feedback loops. An important step in generating rhythmicity is the translocation of clock components into the nucleus, which is regulated in many cases by kinases. In mammals, the kinase promoting the nuclear import of the key clock component Period 2 (PER2) is unknown. Here, we show that the cyclin-dependent kinase 5...
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