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Université de Fribourg

Differential expression of CD31 and von Willebrand factor on endothelial cells in different regions of the human brain: potential implications for cerebral malaria pathogenesis

Mbagwu, Smart Ikechukwu ; Filgueira, Luis

In: Brain Sciences, 2020, vol. 10, no. 1, p. 31

Cerebral microvascular endothelial cells (CMVECs) line the vascular system of the brain and are the chief cells in the formation and function of the blood brain barrier (BBB). These cells are heterogeneous along the cerebral vasculature and any dysfunctional state in these cells can result in a local loss of function of the BBB in any region of the brain. There is currently no report on the...

Consortium of Swiss Academic Libraries

Foot trajectory approximation using the pendulum model of walking

Fang, Juan ; Hunt, Kenneth

In: Medical & Biological Engineering & Computing, 2014, vol. 52, no. 1, p. 45-52

Université de Fribourg

Embodied semantics in a second language: critical review and clinical implications

Monaco, Elisa ; Jost, Lea B. ; Gygax, Pascal M. ; Annoni, Jean-Marie

In: Frontiers in Human Neuroscience, 2019, vol. 13, p. -

The role of the sensorimotor system in second language (L2) semantic processing as well as its clinical implications for bilingual patients has hitherto been neglected. We offer an overview of the issues at stake in this under-investigated field, presenting the theoretical and clinical relevance of studying L2 embodiment and reviewing the few studies on this topic. We highlight that (a) the...

Université de Fribourg

Magneto-responsive cell culture substrates that can be modulated in situ

Crippa, Federica ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 51–54

Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in...

Université de Fribourg

Similarities and differences in altitudinal versus latitudinal variation for morphological traits in Drosophila melanogaster

Klepsatel, Peter ; Gáliková, Martina ; Huber, Christian D. ; Flatt, Thomas

In: Evolution, 2014, vol. 68, no. 5, p. 1385–1398

Understanding how natural environments shape phenotypic variation is a major aim in evolutionary biology. Here, we have examined clinal, likely genetically based variation in morphology among 19 populations of the fruit fly (Drosophila melanogaster) from Africa and Europe, spanning a range from sea level to 3000 m altitude and including locations approximating the southern and northern range...