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Haute Ecole de Gestion & Tourisme

Data mining in Bioprocesses – Knowledge discovery in databases (IIG part)

Artero, Christopher ; Schumann, René (Dir.)

Mémoire de bachelor : Haute Ecole de Gestion & Tourisme, 2021.

The purpose of this thesis is to create clusters from historical data with and without domain knowledge. The method used to cluster the data with domain knowledge is a pattern matching sequence and the method done without domain knowledge is a clustering algorithm that will be defined later. The data had to be retrieved from four old databases, then prepared to be clustered. A...

Université de Fribourg

CO and CO-releasing molecules in medicinal chemistry

Zobi, Fabio

In: Future Medicinal Chemistry, 2013, vol. 5, no. 2, p. 175-188

Since the discovery that CO acts as a cytoprotective and homeostatic molecule, increasing research efforts have been devoted to the exploitation of its therapeutic effects. Both endogenous and exogenous CO improves experimental lung, vascular and cardiac injuries and protects against several inflammatory states. The technology is now in place to bring CO to clinical applications, but the use...

Università della Svizzera italiana

The antibody response to Plasmodium falciparum : cues for vaccine design and the discovery of receptor-based antibodies

Tan, Joshua ; Piccoli, Luca ; Lanzavecchia, Antonio

In: Annual Review of Immunology

P. falciparum remains a serious public health problem and a continuous challenge for the immune system due to the complexity and diversity of the pathogen. Recent advances from several laboratories in the characterization of the antibody response to the parasite have led to the identification of critical targets for protection and revealed a new mechanism of diversification based on the...

Université de Fribourg

French Sufi theopolitics : on the appropriation of the Akbarian concepts of God’s unity, law and perfect man by French modern perennialists

Valentini, Philipp ; Gauthier, François (Dir.)

Thèse de doctorat : Université de Fribourg, 2020.

This dissertation examines the reception of the Andalusian Sufi Ibn ‘Arabī (1165- 1240) by major Francophone Perennialist intellectuals of the twentieth century through an analysis of how they have integrated his teachings into their theopolitical views. The works of René Guénon (1888- 1951), Michel Valsan (1911-1974) and Henry Corbin (1903-1978) are here discussed in light of their...

Université de Fribourg

Complexity and Algorithms for Finding a Perfect Phylogeny from Mixed Tumor Samples

Hujdurovic, Ademir ; Kacar, Ursula ; Milanic, Martin ; Ries, Bernard ; Tomescu, Alexandru I.

In: IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018, vol. 15, no. 1, p. 96-108

Hajirasouliha and Raphael (WABI 2014) proposed a model for deconvoluting mixed tumor samples measured from a collection of high-throughput sequencing reads. This is related to understanding tumor evolution and critical cancer mutations. In short, their formulation asks to split each row of a binary matrix so that the resulting matrix corresponds to a perfect phylogeny and has the minimum...

Université de Fribourg

Colloidal gelation, a means to study elasto-capillarity effects in foam

Mikhailovskaya, Alesya ; Trappe, Véronique ; Salonen, Anniina

In: Soft Matter, 2020, vol. 16, no. 9, p. 2249–2255

We explore the evolution of the mechanical properties of a coarsening foam containing colloidal particles that undergo a sol–gel transition in the continuous phase. This enables us to investigate the impact of elasto-capillarity on foam mechanics over a wide range of elasto-capillary numbers. Right after initiating aggregation the foam mechanics is predominantly determined by the elasticity...

Université de Fribourg

Subfossil lemur discoveries from the Beanka Protected Area in western Madagascar

Burney, David A. ; Andriamialison, Haingoson ; Andrianaivoarivelo, Radosoa A. ; Bourne, Steven ; Crowley, Brooke E. ; Boer, Erik J. de ; Godfrey, Laurie R. ; Goodman, Steven M. ; Griffiths, Christine ; Griffiths, Owen ; Hume, Julian P. ; Joyce, Walter G. ; Jungers, William L. ; Marciniak, Stephanie ; Middleton, Gregory J. ; Muldoon, Kathleen M. ; Noromalala, Eliette ; Pérez, Ventura R. ; Perry, George H. ; Randalana, Roger ; Wright, Henry T.

In: Quaternary Research, 2020, vol. 93, no. 1, p. 187–203

A new fossil site in a previously unexplored part of western Madagascar (the Beanka Protected Area) has yielded remains of many recently extinct vertebrates, including giant lemurs (Babakotia radofilai, Palaeopropithecus kelyus, Pachylemur sp., and Archaeolemur edwardsi), carnivores (Cryptoprocta spelea), the aardvark-like Plesiorycteropus sp., and giant ground cuckoos (Coua). Many of these...

Université de Fribourg

Bicolored Matchings in Some Classes of Graphs

Costa, Marie-Christine ; de Werra, Dominique ; Picouleau, Christophe ; Ries, Bernard

In: Graphs and Combinatorics, 2007, vol. 23, no. 1, p. 47-60

We consider the problem of finding in a graph a set R of edges to be colored in red so that there are maximum matchings having some prescribed numbers of red edges. For regular bipartite graphs with n nodes on each side, we give sufficient conditions for the existence of a set R with |R| = n + 1 such that perfect matchings with k red edges exist for all k, 0 ≤ k ≤ n. Given two integers p...

Université de Fribourg

Claw-free graphs with strongly perfect complements : Fractional and integral version, Part II: Nontrivial strip-structures

Chudnovsky, Maria ; Ries, Bernard ; Zwols, Yori

In: Discrete applied mathematics, 2011, vol. 159, no. 17, p. 1996-2029

Strongly perfect graphs have been studied by several authors (e.g., Berge and Duchet (1984) [1], Ravindra (1984) [7] and Wang (2006) [8]). In a series of two papers, the current paper being the second one, we investigate a fractional relaxation of strong perfection. Motivated by a wireless networking problem, we consider claw-free graphs that are fractionally strongly perfect in the...

Université de Fribourg

Claw-free graphs with strongly perfect complements : Fractional and integral version. Part I. Basic graphs

Chudnovsky, Maria ; Ries, Bernard ; Zwols, Yori

In: Discrete Applied Mathematics, 2011, vol. 159, no. 17, p. 1971-1995

Strongly perfect graphs have been studied by several authors (e.g. Berge and Duchet (1984) [1], Ravindra (1984) [12] and Wang (2006) [14]). In a series of two papers, the current paper being the first one, we investigate a fractional relaxation of strong perfection. Motivated by a wireless networking problem, we consider claw-free graphs that are fractionally strongly perfect in the complement....