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Università della Svizzera italiana

Dissecting human antibody responses: useful, basic and surprising findings

Lanzavecchia, Antonio

In: EMBO molecular medicine, 2018, vol. 10, p. e8879

Human memory B cells and plasma cells represent a rich source of antibodies that have been selected in response to human pathogens. In the last decade, different methods have been developed to interrogate the human memory repertoire and isolate monoclonal antibodies. I will discuss how a target‐agnostic approach based on high‐throughput screening of antibodies produced by cultured B cells...

Université de Fribourg

When black and white make green: the surprising interplay of structure and pigments

Sai, Tianqi ; Wilts, Bodo D. ; Sicher, Alba ; Steiner, Ullrich ; Scheffold, Frank ; Dufresne, Eric R.

In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 47–50

The natural world is teeming with color, which originates either from the wavelength- dependent absorp- tion of light by pigments or from scattering from nanoscale structures, or both. While the latter ' structural color ' has been a topic of intense study in recent years, the most vibrant colors in nature involve contributions from both structure and pigment. The study of structure–pigment...

Université de Fribourg

Founding family ownership, stock market returns, and agency problems

Eugster, Nicolas ; Isakov, Dušan

(Working Papers SES ; 490 (revised))

This paper explores the relationship between founding family ownership and stock market returns. Using the entire population of non-financial firms listed on the Swiss stock market for 2003–2013, we find that the stock returns of family firms are significantly higher than those of non-family firms after adjusting the returns for different firm characteristics and risk factors. Family firms...

Université de Fribourg

Founding family ownership, stock market returns, and agency problems

Eugster, Nicolas ; Isakov, Dušan

(Working Papers SES ; 490)

This paper explores the relationship between founding family ownership and stock market returns. Using the entire population of non-financial firms listed on the Swiss stock market for 2003–2013, we find that the stock returns of family firms are significantly higher than those of non-family firms after adjusting the returns for different risk factors and firm characteristics. Family firms...

Université de Fribourg

Surprising lack of liposome-induced complement activation by artificial 1,3-diamidophospholipids in vitro

Bugna, Simon ; Buscema, Marzia ; Matviykiv, Sofiya ; Urbanics, Rudolf ; Weinberger, Andreas ; Meszaros, Tamas ; Szebeni, Janos ; Zumbuehl, Andreas ; Saxer, Till ; Müller, Bert

In: Nanomedicine: Nanotechnology, Biology and Medicine, 2016, vol. 12, no. 3, p. 845–849

Cardio-vascular diseases are the main cause of death, emphasizing the need to improve patient treatment and survival. One therapeutic approach is a liposome-based drug carrier system specifically targeting constricted arteries. The recently discovered mechano-sensitive liposomes use hemodynamic shear-stress differences between healthy and constricted blood vessels as trigger for drug release....

Haute école de gestion de Genève

Analysis of the assessment of risks related to working conditions in mines and how to improve it

Läuchli, Evelyne ; Fragnière, Emmanuel (Dir.)

Mémoire de bachelor : Haute école de gestion de Genève, 2014 ; TDEE 236.

Metals and Minerals are commodities essential to the development of a country and to the survival of an individual, but the press relates relatively often tragic accidents happening in mines. Moreover, NGOs and other organisations regularly point the finger to the practices of the extractive industry in terms of sustainability. Therefore I wanted to see what the reality was and why companies...

Bibliothèque cantonale jurassienne

Extending the radiocarbon calibration beyond 26,000 years before present using fossil corals

Chiu, Tzu-chien

In: Quaternary science reviews : the international multidisciplinary research and review journal, 2005, vol. 24, p. 1797-1808