Université de Fribourg

Hydrogen bond guidance and aromatic stacking drive liquid-liquid phase separation of intrinsically disordered histidine-rich peptides

Gabryelczyk, Bartosz ; Cai, Hao ; Shi, Xiangyan ; Sun, Yue ; Swinkels, Piet J.M. ; Salentinig, Stefan ; Pervushin, Konstantin ; Miserez, Ali

In: Nature Communications, 2019, vol. 10, no. 1, p. 1–12

Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) is involved in both intracellular membraneless organelles and extracellular tissues. Despite growing understanding of LLPS, molecular-level mechanisms behind this process are still not fully established. Here, we use histidine-rich squid beak proteins (HBPs) as model IDPs to shed light on molecular interactions...

Université de Fribourg

Male mutation bias is the main force shaping chromosomal substitution rates in monotreme mammals

Link, Vivian ; Aguilar-Gómez, Diana ; Ramírez-Suástegui, Ciro ; Hurst, Laurence D. ; Cortez, Diego

In: Genome Biology and Evolution, 2017, vol. 9, no. 9, p. 2198–2210

In many species, spermatogenesis involves more cell divisions than oogenesis, and the male germline, therefore, accumulates more DNA replication errors, a phenomenon known as male mutation bias. The extent of male mutation bias (α) is estimated by comparing substitution rates of the X, Y, and autosomal chromosomes, as these chromosomes spend different proportions of their time in the...

Bibliothèque cantonale jurassienne

The socio-sexual behaviour of extant archosaurs : implications for understanding dinosaur behaviour

Isles, Timothy E.

In: Historical biology : an international journal of paleobiology, 2009, vol. 21, no. 3-4, p. 139-214

Bibliothèque cantonale jurassienne

A new basal ornithopod dinosaur from the Upper Cretaceous of South Korea

Huh, Min

In: Neues Jahrbuch für Geologie und Paläontologie. Abhandlungen, 2010, vol. 259, no. 1, p. 1-24

Bibliothèque cantonale jurassienne

Dinosaur lactation ?

Else, Paul L.

In: Journal of experimental biology, 2013, vol. 216, p. 1-5