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Université de Fribourg

Circadian and genetic modulation of visually-guided navigation in Drosophila larvae

Asirim, Ece Z. ; Humberg, Tim-Henning ; Maier, G. Larisa ; Sprecher, Simon G.

In: Scientific Reports, 2020, vol. 10, no. 1, p. 2752

Organisms possess an endogenous molecular clock which enables them to adapt to environmental rhythms and to synchronize their metabolism and behavior accordingly. Circadian rhythms govern daily oscillations in numerous physiological processes, and the underlying molecular components have been extensively described from fruit flies to mammals. Drosophila larvae have relatively simple nervous...

Università della Svizzera italiana

A novel interaction between the TLR7 and a colchicine derivative revealed through a computational and experimental study

Gentile, Francesco ; Deriu, Marco A. ; Barakat, Khaled ; Danani, Andrea ; Tuszynski, Jack

In: Pharmaceuticals, 2018, vol. 11, no. 1, p. 22

The Toll-Like Receptor 7 (TLR7) is an endosomal membrane receptor involved in the innate immune system response. Its best-known small molecule activators are imidazoquinoline derivatives such as imiquimod (R-837) and resiquimod (R-848). Recently, an interaction between R-837 and the colchicine binding site of tubulin was reported. To investigate the possibility of an interaction between...

Université de Fribourg

Fossil amphibians and reptiles from the Neogene locality of Maramena (Greece), the most diverse European herpetofauna at the Miocene/Pliocene transition boundary

Georgalis, Georgios L. ; Villa, Andrea ; Ivanov, Martin ; Vasilyan, Davit ; Delfino, Massimo

In: Palaeontologia Electronica, 2019, p. -

We herein describe the fossil amphibians and reptiles from the Neogene (latest Miocene or earliest Pliocene; MN 13/14) locality of Maramena, in northern Greece. The herpetofauna is shown to be extremely diverse, comprising at least 30 different taxa. Amphibians include at least six urodelan (Cryptobranchidae indet., Salamandrina sp., Lissotriton sp. [Lissotriton vulgaris group], Lissotriton sp.,...

Université de Fribourg

A review of the fossil record of nonbaenid turtles of the clade Paracryptodira

Joyce, Walter G. ; Anquetin, Jérémy

In: Bulletin of the Peabody Museum of Natural History, 2019, vol. 60, no. 2, p. 129–155

The fossil record of nonbaenid paracryptodires ranges from the Late Jurassic (Kimmeridgian) to the Paleocene of North America and Europe only. Earlier remains may be present as early as the Middle Jurassic (Bathonian). Only a single dispersal event is documented between the two continents after their breakup during the Cretaceous in the form of the appearance of the Compsemys lineage in the ...

Université de Fribourg

Early Miocene herpetofaunas from the Greek localities of Aliveri and Karydia – bridging a gap in the knowledge of amphibians and reptiles from the early Neogene of southeastern Europe

Georgalis, Georgios L. ; Villa, Andrea ; Ivanov, Martin ; Roussiakis, Socrates ; Skandalos, Panagiotis ; Delfino, Massimo

In: Historical Biology, 2019, vol. 31, no. 8, p. 1045–1064

We here describe new remains of amphibians and reptiles from the early Miocene (MN 4) of two different Greek localities, Aliveri and Karydia. The newly described material consists of urodelans, alytids, indeterminate anurans, turtles, crocodylians, lacertids, indeterminate scincomorphs, anguids, colubrids, viperids, and indeterminate snakes. The presence of the frog Latonia cf. gigantea in...

Université de Fribourg

Does being assigned to a low school track negatively affect psychological adjustment?

Müller, Christoph Michael ; Hofmann, Verena

In: School Effectiveness and School Improvement, 2016, vol. 27, p. 95-115

Previous research suggests that the 1st year in secondary school for some students goes hand in hand with an increase in adjustment difficulties. One factor that might influence this process on an individual, compositional, and institutional level is the academic track a student attends. It was hypothesized that being assigned to a lowqualifying track predicts a stronger increase in...

Université de Fribourg

Fossil amphibians and reptiles from Plakias, Crete: A glimpse into the earliest late Miocene herpetofaunas of southeastern Europe

Georgalis, Georgios L. ; Villa, Andrea ; Vlachos, Evangelos ; Delfino, Massimo

In: Geobios, 2016, vol. 49, no. 6, p. 433–444

Fossil amphibians and reptiles from the earliest late Miocene (early Tortonian, MN 9) of Plakias (Crete, Greece) are described in this paper. Most of the material is fragmentary, precluding precise taxonomic assignment. Nevertheless, the herpetofauna of Plakias is here shown to be diverse, comprising at least six different taxa: an alytid anuran, a crocodilian, two turtles (a pan-trionychid...

Université de Fribourg

Early Miocene gastropod and ectothermic vertebrate remains from the Lesvos Petrified Forest (Greece)

Vasileiadou, Katerina ; Böhme, Madelaine ; Neubauer, Thomas A. ; Georgalis, Georgios L. ; Syrides, George E. ; Papadopoulou, Lambrini ; Zouros, Nickolas

In: PalZ, 2017, vol. 91, no. 4, p. 541–564

The Lesvos Petrified Forest (western Lesvos, Greece) has long been famous for its plant fossils. Recently, one proboscidean (from the Gavathas locality) and seven micromammalian species (from the Lapsarna locality) were described; these were the first animals to be found in the Early Miocene subtropical forest. For the first time, a fauna of gastropods and ectothermic vertebrates from the...