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Università della Svizzera italiana

A hierarchy of graph-based methods to study the behavior of immune cells in vivo

Pizzagalli, Diego Ulisse ; Krause, Rolf (Dir.) ; Gonzalez, Santiago Fernandez (Codir.)

Thèse de doctorat : Università della Svizzera italiana, 2020 ; 2020INFO018.

The immune system has a critical role in diseases of primary importance such as infections and cancer. Hence, it represents a target for novel therapeutic strategies. However, the immune system relies on a complex network of cell-to-cell interactions which remains largely unknown, or difficult to be interpreted. The combination of experimental data with computational methods is of paramount...

Université de Fribourg

Fish, amphibian and reptilian assemblage from the middle Miocene locality Gračanica—Bugojno palaeolake, Bosnia and Herzegovina

Vasilyan, Davit

In: Palaeobiodiversity and Palaeoenvironments, 2020, vol. 100, no. 2, p. 437–455

This paper presents the first fossil fish, amphibian and reptilian fauna from Bosnia and Herzegovina Dinarides. The fauna of ectothermic vertebrates of the Bugojno palaeolake, dated to 15.2–14.0 Ma, composes of killifishes (Cyprinodontiformes indet.), a barb (Barbini indet. (aff. Barbus), a crocodile newt (Chelotriton sp.), a painted frog (Latonia sp.) and a crocodile (Alligatoroidea indet....

Université de Fribourg

Impact of bottom water currents on benthic foraminiferal assemblages in a cold-water coral environment: The Moira Mounds (NE Atlantic)

Fentimen, Robin ; Lim, Aaron ; Rüggeberg, Andres ; Wheeler, Andrew J. ; Rooij, David Van ; Foubert, Anneleen

In: Marine Micropaleontology, 2020, vol. 154, p. 101799

Strong bottom currents play a key role in cold-water coral environments by shaping their morphology and providing the necessary food for the corals to thrive. This study investigates the differences between living and dead benthic foraminiferal assemblages in such environments, more precisely on the Moira Mounds (NE Atlantic). A specific focus is to understand the role of currents and their...

Université de Fribourg

Late Jurassic theropod dinosaur bones from the Langenberg Quarry (Lower Saxony, Germany) provide evidence for several theropod lineages in the central European archipelago

Evers, Serjoscha W. ; Wings, Oliver

In: PeerJ, 2020, vol. 8, p. e8437

Marine limestones and marls in the Langenberg Quarry provide unique insights into a Late Jurassic island ecosystem in central Europe. The beds yield a varied assemblage of terrestrial vertebrates including extremely rare bones of theropod from theropod dinosaurs, which we describe here for the first time. All of the theropod bones belong to relatively small individuals but represent a wide...

Université de Fribourg

Understanding of object rotation between two and three years of age

Pedrett, Salome ; Kaspar, Lea ; Frick, Andrea

In: Developmental Psychology, 2020, vol. 56, p. 261-274

Toddlers’ understanding of object rotation was investigated using a multi-method approach. Participants were 44 toddlers between 22 and 38 months of age. In an eye-tracking task, they observed a shape that rotated and disappeared briefly behind an occluder. In an object-fitting task, they rotated wooden blocks and fit them through apertures. Results of the eye-tracking task showed that with...

Université de Fribourg

A conceptual framework for range-expanding species that track human-induced environmental change

Essl, Franz ; Dullinger, Stefan ; Genovesi, Piero ; Hulme, Philip E ; Jeschke, Jonathan M ; Katsanevakis, Stelios ; Kühn, Ingolf ; Lenzner, Bernd ; Pauchard, Aníbal ; Pyšek, Petr ; Rabitsch, Wolfgang ; Richardson, David M ; Seebens, Hanno ; van Kleunen, Mark ; van der Putten, Wim H ; Vilà, Montserrat ; Bacher, Sven

In: BioScience, 2019, vol. 69, no. 11, p. 908–919

For many species, human-induced environmental changes are important indirect drivers of range expansion into new regions. We argue that it is important to distinguish the range dynamics of such species from those that occur without, or with less clear, involvement of human-induced environmental changes. We elucidate the salient features of the rapid increase in the number of species whose...

Université de Fribourg

Aubenas-les-Alpes (S-E France). Part III – Last and final part of the mammalian assemblage with some comments on the palaeoenvironment and palaeobiogeography = Aubenas-les-Alpes (S-E France). Part III – Dernière partie de l’assemblage mammalien avec quelques commentaires sur le paléoenvironnement et la paléobiogéographie

Maridet, Olivier ; Hugueney, Marguerite ; Costeur, Loïc

In: Annales de Paléontologie, 2019, vol. 105, no. 2, p. 139–153

L’étude du nouveau matériel issu d’Aubenas-les-Alpes permet de compléter la liste faunique par des taxa jusqu’alors inconnus dans cette localité (Neurogymnurus cayluxi, Issiodoromys minor, Eomys minor, Pseudocricetodon cf. hausi, Pseudocricetodon aff. philippi). Les nouveaux spécimens de la musaraigne Srinitium marteli améliorent notre connaissance de ce rare insectivore. Les...

Université de Fribourg

Does being assigned to a low school track negatively affect psychological adjustment?

Müller, Christoph Michael ; Hofmann, Verena

In: School Effectiveness and School Improvement, 2016, vol. 27, p. 95-115

Previous research suggests that the 1st year in secondary school for some students goes hand in hand with an increase in adjustment difficulties. One factor that might influence this process on an individual, compositional, and institutional level is the academic track a student attends. It was hypothesized that being assigned to a lowqualifying track predicts a stronger increase in...

Università della Svizzera italiana

Leukocyte tracking database, a collection of immune cell tracks from intravital 2-photon microscopy videos

Pizzagalli, Diego Ulisse ; Farsakoglu, Yagmur ; Palomino-Segura, Miguel ; Palladino, Elisa ; Sintes, Jordi ; Marangoni, Francesco ; Mempel, Thorsten R. ; Koh, Wan Hon ; Murooka, Thomas T. ; Thelen, Flavian ; Stein, Jens V. ; Pozzi, Giuseppe ; Marcus Thelen ; Krause, Rolf ; Gonzalez, Santiago Fernandez

In: Scientific data, 2018, vol. 5, p. 180129

Recent advances in intravital video microscopy have allowed the visualization of leukocyte behavior in vivo, revealing unprecedented spatiotemporal dynamics of immune cell interaction. However, state-of-the-art software and methods for automatically measuring cell migration exhibit limitations in tracking the position of leukocytes over time. Challenges arise both from the complex migration...

Université de Fribourg

Introducing otree_tools : A powerful package to provide process data for attention, multitasking behavior and effort through tracking focus

Chapkovski, Philipp ; Zihlmann, Christian

In: Journal of behavioral and experimental finance, 2019, vol. 23, p. 75-83

With the advent of online subject pools, conducting experiments outside thelaboratory has become more popular among the scientific community. Unlike the lab, online and field environments tend to be accompanied by a loss of control. In this article we introduce otree_tools, a concise yet powerful add-on for oTree (Chen et al., 2016).otree_tools provides novel ways by which to measure...