In: Bernoulli, 2020, vol. 26, no. 3, p. 1665–1705
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In: Antimicrobial Agents and Chemotherapy, 2020, vol. 64, no. 8, p. -
KPC-50 is a KPC-3 variant identified from a Klebsiella pneumoniae clinical isolate recovered in Switzerland in 2019. Compared to KPC-3, KPC-50 shows (i) a three- amino-acid insertion (Glu-Ala-Val) between amino acids 276 and 277, (ii) an increased affinity to ceftazidime, (iii) a decreased sensitivity to avibactam, explaining the ceftazidime-avibactam resistance, and (iv) an association with a...
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In: Biosensors and Bioelectronics, 2020, vol. 167, p. 112494
G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich DNA or RNA. The conformation and function of G-quadruplex are determined by a number of factors, including the number and polarity of nucleotide strands, the type of cations and the binding targets. Recent studies led to the discovery of additional advantageous attributes of G-quadruplex with the...
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In: The Cryosphere, 2020, vol. 14, no. 3, p. 1043–1050
Comprehensive assessments of global glacier mass changes based on a variety of observations and prevailing methodologies have been published at multi-annual intervals. For the years in between, the glaciological method provides annual observations of specific mass changes but is suspected to not be representative at the regional to global scales due to uneven glacier distribution with...
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In: Scientific Reports, 2020, vol. 10, p. 5051
Cenozoic ectothermic continental tetrapods (amphibians and reptiles) have not been documented previously from Antarctica, in contrast to all other continents. Here we report a fossil ilium and an ornamented skull bone that can be attributed to the Recent, South American, anuran family Calyptocephalellidae or helmeted frogs, representing the first modern amphibian found in Antarctica. The two bone...
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In: Palaeobiodiversity and Palaeoenvironments, 2019, vol. 99, no. 4, p. 723–757
In this paper, we describe ectothermic vertebrate assemblages from the Kargı 1, Kargı 2, Kargı 3, Harami1, Harami 3, Hancılı, Keseköy, Çandır and Bağiçi localities in Turkey. The ages of these localities range from the latest Oligocene to the middle Miocene. The preserved non-mammalian fauna of the studied localities includes fishes (Luciobarbus sp., Barbus sp., Luciobarbus vel...
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In: Plos one, 2014, vol. 9, no. 7, p. e102658
In this manuscript, we modulate the binding properties of estrogen receptor protein by rationally modifying the amino acid composition of its ligand binding domain. By combining sequence alignment and structural analysis of known estrogen receptor- ligand complexes with computational analysis, we were able to predict estrogen receptor mutants with altered binding properties. These predictions...
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In: PeerJ, 2018, vol. 6, p. e5511
Background Amphibians, due to their ecophysiological peculiarities, have a physiology dependent on environmental conditions and sensitively respond to their changes. Here, the oldest record of the genus Thaumastosaurus is described, whose fossil record known exclusively from Western Europe is discussed in the scope of the climatic changes of 33.5–40.5 Ma. Results In the present paper, the...
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In: Probability Theory and Related Fields, 2011, vol. 151, no. 3-4, p. 591-611
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In: Eclogae Geologicae Helvetiae, 2006, vol. 99, no. 2, p. 157-174
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