Affiner les résultats

Collection spécifique

Langue

Université de Fribourg

An in vitro lung system to assess the proinflammatory hazard of carbon nanotube aerosols

Barosova, Hana ; Karakocak, Bedia Begum ; Septiadi, Dedy ; Petri-Fink, Alke ; Stone, Vicki ; Rothen-Rutishauser, Barbara

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 15, p. 5335

In vitro three-dimensional (3D) lung cell models have been thoroughly investigated in recent years and provide a reliable tool to assess the hazard associated with nanomaterials (NMs) released into the air. In this study, a 3D lung co-culture model was optimized to assess the hazard potential of multiwalled carbon nanotubes (MWCNTs), which is known to provoke inflammation and fibrosis,...

Université de Fribourg

Rapid and sensitive quantification of cell-associated multi-walled carbon nanotubes

Steinmetz, Lukas ; Bourquin, Joel ; Barosova, Hana ; Haeni, Laetitia ; Caldwell, Jessica ; Milosevic, Ana ; Geers, Christoph ; Bonmarin, Mathias ; Taladriz-Blanco, Patricia ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: Nanoscale, 2020, vol. 12, no. 33, p. 17362–17372

Evaluating nanomaterial uptake and association by cells is relevant for in vitro studies related to safe-by-design approaches, nanomedicine or applications in photothermal therapy. However, standard analytical techniques are time-consuming, involve complex sample preparation or include labelling of the investigated sample system with e.g. fluorescent dyes. Here, we explore lock-in...

Université de Fribourg

One-step ring opening metathesis block-like copolymers and their compositional analysis by a novel retardation technique

Yasir, Mohammad ; Liu, Peng ; Markwart, Jens C. ; Suraeva, Oksana ; Wurm, Frederik R. ; Smart, Jansie ; Lattuada, Marco ; Kilbinger, Andreas F. M.

In: Angewandte Chemie International Edition, 2020, vol. 59, no. 32, p. 13597-13601

Using a one-step synthetic route for block copolymers avoids the repeated addition of monomers to the polymerization mixture, which can easily lead to contamination and, therefore, to the unwanted termination of chain growth. For this purpose, monomers (M1–M5) with different steric hindrances and different propagation rates are explored. Copolymerization of M1 (propagating rapidly) with M2...

Consortium of Swiss Academic Libraries

Poly-acrylic Acid Brushes and Adsorbed Proteins

Reinhardt, Matthias ; Kreuzer, Martin ; Geue, Thomas ; Dahint, Reiner ; Ballauff, Matthias ; Steitz, Roland

In: Zeitschrift für Physikalische Chemie, 2015, vol. 229, no. 7-8, p. 1119-1139