Université de Fribourg

Hierarchically porous reduced graphene oxide coated with metal–organic framework hkust-1 for enhanced hydrogen gas affinity

Song, Kyung Seob ; Kim, Daeok ; Coskun, Ali

In: ACS Applied Nano Materials, 2020, vol. 3, no. 2, p. 985–991

Metal–organic frameworks (MOFs) are crystalline porous materials that have been actively explored for various gas storage, separation, and conversion applications because of their structural tunability. While the micropores (<2 nm) in MOFs are essential for increased gas affinity, these small pores significantly decrease the mass-transport kinetics. One way to address this challenge is to ...

Université de Fribourg

Nitrogen-doped carbons with hierarchical porosity via chemical blowing towards long-lived metal-free catalysts for acetylene hydrochlorination

Kaiser, Selina K. ; Song, Kyung Seob ; Mitchell, Sharon ; Coskun, Ali ; Pérez‐Ramírez, Javier

In: ChemCatChem, 2020, vol. 12, no. 7, p. 1922-1925

Porous nitrogen‐doped carbons (NCs) are sustainable alternatives to the toxic mercury‐based acetylene hydrochlorination catalysts applied in the manufacture of polyvinyl chloride. However, the application of NCs as metal‐free catalysts is hampered by their insufficient durability under industrially relevant process conditions. In particular, pore blockage leads to accelerated...

Université de Fribourg

Bimetallic metal organic frameworks with precisely positioned metal centers for efficient H2 storage

Kim, Daeok ; Song, Kyung Seob ; Buyukcakir, Onur ; Yildirim, Taner ; Coskun, Ali

In: Chemical Communications, 2018, vol. 54, no. 86, p. 12218–12221

We demonstrated that the ratio and position of two different metal ions, Pd and Cu, can be precisely controlled within MOFs through predesigned metal clusters. These MOF structures incorporating Pd–Cu paddle wheel units were synthesised simply by reacting Pd–Cu acetate metal clusters and tritopic organic linkers at room temperature. Pd–Cu open metal sites were found to be uniformly...

Université de Fribourg

Development and clinical validation of a blood test based on 29-gene expression for early detection of colorectal cancer

Ciarloni, Laura ; Ehrensberger, Sahar Hosseinian ; Imaizumi, Natsuko ; Monnier-Benoit, Sylvain ; Nichita, Cristina ; Myung, Seung-Jae ; Kim, Joo Sung ; Song, Si Young ; Kim, Tae Il ; Weg, Boudewijn van der ; Meier, Rémy ; Borovicka, Jan ; Beglinger, Christoph ; Vallet, Cédric ; Maerten, Philippe ; Rüegg, Curzio ; Dorta, Gian

In: Clinical Cancer Research, 2016, p. -

A blood test for colorectal cancer (CRC) screening is a valuable tool to for testing asymptomatic individuals and reducing CRC-related mortality. The objective of this study was to develop and validate a novel blood test able to differentiate patients with CRC and adenomatous polyps (AP) from individuals with a negative colonoscopy. Experimental Design: A case-control, multicenter clinical...

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