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Preventing implant-associated infections by silver coating

Kuehl, Richard ; Brunetto, Priscilla S. ; Woischnig, Anne-Kathrin ; Varisco, Massimo ; Rajacic, Zarko ; Vosbeck, Juerg ; Terracciano, Luigi ; Fromm, Katharina M. ; Khanna, Nina

In: Antimicrobial Agents and Chemotherapy, 2016, p. AAC.02934–15

Implant-associated infections (IAI) are a dreaded complication mainly caused by biofilm-forming staphylococci. Implant surfaces preventing microbial colonization would be desirable. We examined the preventive effect of a silver-coated titanium aluminium niobium (TiAlNb) alloy. The surface elicited a strong, inoculum-dependent activity against Staphylococcus (S.) epidermidis and S. aureus in an...