Université de Fribourg

Absorb bioresorbable scaffold versus xience metallic stent for prevention of restenosis following percutaneous coronary intervention in patients at high risk of restenosis: rationale and design of the COMPARE ABSORB trial

Chang, Chun Chin ; Onuma, Yoshinobu ; Achenbach, Stephan ; Barbato, Emanuele ; Chevalier, Bernard ; Cook, Stéphane ; Dudek, Dariusz ; Escaned, Javier ; Gori, Tommaso ; Kočka, Viktor ; Tarantini, Giuseppe ; E.J.West, Nick ; Morice, Marie-Claude ; G.P.Tijssen, Jan ; Geuns, Robert-Janvan ; C.Smits, Pieter

In: Cardiovascular Revascularization Medicine, 2019, vol. 20, no. 7, p. 577–582

Background: The advent of bioresorbable vascular scaffolds (BVS) was considered as a potential improvement in percutaneous coronary intervention (PCI) after the groundbreaking development of drug eluting stents (DES). However, the clinical performance, long-term safety and efficacy of BVS in complex coronary lesions remain uncertain. COMPARE ABSORB, a multicenter, single blind, prospective ...

Université de Fribourg

Coronary evaginations and peri-scaffold aneurysms following implantation of bioresorbable scaffolds: incidence, outcome, and optical coherence tomography analysis of possible mechanisms

Gori, Tommaso ; Jansen, Thomas ; Weissner, Melissa ; Foin, Nicolas ; Wenzel, Philip ; Schulz, Eberhard ; Cook, Stéphane ; Münzel, Thomas

In: European Heart Journal, 2016, vol. 37, no. 26, p. 2040–2049

Background Peri-stent coronary evaginations may disturb flow and have been proposed as possible risk factor for late stent thrombosis. We describe incidence, predictors, and possible mechanisms of coronary evaginations 12 months after implantation of bioresorbable vascular scaffolds (BVS).Methods and results One hundred and two BVS implanted in 90 patients...

Université de Fribourg

Bioresorbable coronary scaffold thrombosis: multicenter comprehensive analysis of clinical presentation, mechanisms, and predictors

Puricel, Serban ; Cuculi, Florim ; Weissner, Melissa ; Schmermun, Axel ; Jamshidi, Peiman ; Nyffenegger, Tobias ; Binder, Harald ; Eggebrecht, Holger ; Münzel, Thomas ; Cook, Stéphane ; Gori, Tommaso

In: Journal of the American College of Cardiology, 2016, vol. 67, no. 8, p. 921–931

Background Recent reports suggest an elevated incidence of bioresorbable vascular scaffold (BVS) thrombosis (scaffold thrombosis [ScT]).Objectives This study investigated occurrence rates, clinical and angiographic characteristics, and possible mechanisms of ScT in all-comer patients undergoing BVS implantation at 2 German and 2 Swiss hospitals.Methods A total of 1,305 consecutive patients...

Université de Fribourg

Optical coherence tomography findings in bioresorbable vascular scaffolds thrombosis

Cuculi, Florim ; Puricel, Serban ; Jamshidi, Peiman ; Valentin, Jérémy ; Kallinikou, Zacharenia ; Toggweiler, Stefan ; Weissner, Melissa ; Münzel, Thomas ; Cook, Stéphane ; Gori, Tommaso

In: Circulation: Cardiovascular Interventions, 2015, vol. 8, no. 10, p. e002518

Background—Everolimus-eluting bioresorbable vascular scaffolds have been developed to improve late outcomes after coronary interventions. However, recent registries raised concerns regarding an increased incidence of scaffold thrombosis (ScT). The mechanism of ScT remains unknown.Methods and Results—The present study investigated angiographic and optical...