Université de Fribourg

Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity

Kuhn, Benjamin M. ; Nodzyński, Tomasz ; Errafi, Sanae ; Bucher, Rahel ; Gupta, Shibu ; Aryal, Bibek ; Dobrev, Petre ; Bigler, Laurent ; Geisler, Markus ; Zažímalová, Eva ; Friml, Jiří ; Ringli, Christoph

In: Scientific Reports, 2017, vol. 7, p. 41906

The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Flavonols have been shown to alter auxin transport activity and changes in...

Université de Fribourg

TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics

Zhu, Jinsheng ; Bailly, Aurelien ; Zwiewka, Marta ; Sovero, Valpuri ; Donato, Martin Di ; Ge, Pei ; Oehri, Jacqueline ; Aryal, Bibek ; Hao, Pengchao ; Linnert, Miriam ; Burgardt, Noelia Inés ; Lücke, Christian ; Weiwad, Matthias ; Michel, Max ; Weiergräber, Oliver H. ; Pollmann, Stephan ; Azzarello, Elisa ; Mancuso, Stefano ; Ferro, Noel ; Fukao, Yoichiro ; Hoffmann, Céline ; Wedlich-Söldner, Roland ; Friml, Jiří ; Thomas, Clément ; Geisler, Markus

In: The Plant Cell, 2016, vol. 28, no. 4, p. 930–948

Plant growth and architecture is regulated by the polar distribution of the hormone auxin. Polarity and flexibility of this process is provided by constant cycling of auxin transporter vesicles along actin filaments, coordinated by a positive auxin-actin feedback loop. Both polar auxin transport and vesicle cycling are inhibited by synthetic auxin transport inhibitors, such as...

Université de Fribourg

The cyclophilin A DIAGEOTROPICA gene affects auxin transport in both root and shoot to control lateral root formation

Ivanchenko, Maria G. ; Zhu, Jinsheng ; Wang, Bangjun ; Medvecká, Eva ; Du, Yunlong ; Azzarello, Elisa ; Mancuso, Stefano ; Megraw, Molly ; Filichkin, Sergei ; Dubrovsky, Joseph G. ; Friml, Jiří ; Geisler, Markus

In: Development, 2015, p. dev.113225

Cyclophilin A is a conserved peptidyl-prolyl cis-trans isomerase (PPIase) best known as the cellular receptor of the immunosuppressant cyclosporine A. Despite significant effort, evidence of developmental functions of cyclophilin A in non-plant systems has remained obscure. Mutations in a tomato (Solanum lycopersicum) cyclophilin A ortholog, DIAGEOTROPICA (DGT), have been shown to abolish the...

Université de Fribourg

WOX5–IAA17 feedback circuit-mediated cellular auxin response is crucial for the patterning of root stem cell niches in Arabidopsis

Tian, Huiyu ; Wabnik, Krzysztof ; Niu, Tiantian ; Li, Hanbing ; Yu, Qianqian ; Pollmann, Stephan ; Vanneste, Steffen ; Govaerts, Willy ; Rolčík, Jakub ; Geisler, Markus ; Friml, Jiří ; Ding, Zhaojun

In: Molecular Plant, 2014, vol. 7, no. 2, p. 277–289

In plants, the patterning of stem cell-enriched meristems requires a graded auxin response maximum that emerges from the concerted action of polar auxin transport, auxin biosynthesis, auxin metabolism, and cellular auxin response machinery. However, mechanisms underlying this auxin response maximum-mediated root stem cell maintenance are not fully understood. Here, we present unexpected evidence...

Université de Fribourg

Expression of TWISTED DWARF1 lacking its in-plane membrane anchor leads to increased cell elongation and hypermorphic growth

Bailly, Aurélien ; Wang, Bangjun ; Zwiewka, Marta ; Pollmann, Stephan ; Schenck, Daniel ; Lüthen, Hartwig ; Schulz, Alexander ; Friml, Jiri ; Geisler, Markus

In: The Plant Journal, 2014, vol. 77, no. 1, p. 108–118

Plant growth is achieved predominantly by cellular elongation, which is thought to be controlled on several levels by apoplastic auxin. Auxin export into the apoplast is achieved by plasma membrane efflux catalysts of the PIN-FORMED (PIN) and ATP-binding cassette protein subfamily B/phosphor-glycoprotein (ABCB/PGP) classes; the latter were shown to depend on interaction with the FKBP42, TWISTED...

Université de Fribourg

Arabidopsis TWISTED DWARF1 functionally interacts with auxin exporter ABCB1 on the root plasma membrane

Wang, Bangjun ; Bailly, Aurélien ; Zwiewka, Marta ; Henrichs, Sina ; Azzarello, Elisa ; Mancuso, Stefano ; Maeshima, Masayoshi ; Friml, Jiří ; Schulz, Alexander ; Geisler, Markus

In: The Plant Cell, 2013, vol. 25, no. 1, p. 202-214

Plant architecture is influenced by the polar, cell-to-cell transport of auxin that is primarily provided and regulated by plasma membrane efflux catalysts of the PIN-FORMED and B family of ABC transporter (ABCB) classes. The latter were shown to require the functionality of the FK506 binding protein42 TWISTED DWARF1 (TWD1), although underlying mechanisms are unclear. By genetic manipulation of...

Université de Fribourg

ER-localized auxin transporter PIN8 regulates auxin homeostasis and male gametophyte development in Arabidopsis

Ding, Zhaojun ; Wang, Bangjun ; Moreno, Ignacio ; Dupláková, Nikoleta ; Simon, Sibu ; Carraro, Nicola ; Reemmer, Jesica ; Pěnčík, Aleš ; Chen, Xu ; Tejos, Ricardo ; Skůpa, Petr ; Pollmann, Stephan ; Mravec, Jozef ; Petrášek, Jan ; Zažímalová, Eva ; Honys, David ; Rolčík, Jakub ; Murphy, Angus ; Orellana, Ariel ; Geisler, Markus ; Friml, Jiří

In: Nature Communications, 2012, p. -

Auxin is a key coordinative signal required for many aspects of plant development and its levels are controlled by auxin metabolism and intercellular auxin transport. Here we find that a member of PIN auxin transporter family, PIN8 is expressed in male gametophyte of Arabidopsis thaliana and has a crucial role in pollen development and functionality. Ectopic expression in sporophytic tissues...

Université de Fribourg

A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants

Barbez, Elke ; Kubeš, Martin ; Rolčík, Jakub ; Béziat, Chloé ; Pěnčík, Aleš ; Wang, Bangjun ; Rosquete, Michel Ruiz ; Zhu, Jinsheng ; Dobrev, Petre I. ; Lee, Yuree ; Zažímalovà, Eva ; Petrášek, Jan ; Geisler, Markus ; Friml, Jiří ; Kleine-Vehn, Jürgen

In: Nature, 2012, p. -

The phytohormone auxin acts as a prominent signal, providing, by its local accumulation or depletion in selected cells, a spatial and temporal reference for changes in the developmental program. The distribution of auxin depends on both auxin metabolism (biosynthesis, conjugation and degradation) and cellular auxin transport. We identified in silico a novel putative auxin transport facilitator...

Voir aussi: noms d'auteurs similaires
9 Friml, Jiri
9 Friml, Jiří