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Université de Fribourg

Differential patterns of functional and structural plasticity within and between inferior frontal gyri support training-induced improvements in inhibitory control proficiency

Chavan, Camille F. ; Mouthon, Michael ; Draganski, Bogdan ; Zwaag, Wietske van der ; Spierer, Lucas

In: Human Brain Mapping, 2015, vol. 36, no. 7, p. 2527–2543

Ample evidence indicates that inhibitory control (IC), a key executive component referring to the ability to suppress cognitive or motor processes, relies on a right-lateralized fronto-basal brain network. However, whether and how IC can be improved with training and the underlying neuroplastic mechanisms remains largely unresolved. We used functional and structural magnetic resonance imaging to...

Université de Fribourg

Early attentional processes distinguish selective from global motor inhibitory control: An electrical neuroimaging study

Sallard, Etienne ; Barral, Jérôme ; Chavan, Camille F. ; Spierer, Lucas

In: NeuroImage, 2014, vol. 87, p. 183–189

The rapid stopping of specific parts of movements is frequently required in daily life. Yet, whether selective inhibitory control of movements is mediated by a specific neural pathway or by the combination between a global stopping of all ongoing motor activity followed by the re-initiation of task-relevant movements remains unclear. To address this question, we applied time-wise statistical...

Université de Fribourg

Contributions of pitch and bandwidth to sound-induced enhancement of visual cortex excitability in humans

Spierer, Lucas ; Manuel, Aurelie L. ; Bueti, Domenica ; Murray, Micah M.

In: Cortex, 2014, vol. 49, no. 10, p. 2728–2734

Multisensory interactions have been documented within low-level, even primary, cortices and at early post-stimulus latencies. These effects are in turn linked to behavioral and perceptual modulations. In humans, visual cortex excitability, as measured by transcranial magnetic stimulation (TMS) induced phosphenes, can be reliably enhanced by the co-presentation of sounds. This enhancement occurs...

Université de Fribourg

Age-related changes in the bimanual advantage and in brain oscillatory activity during tapping movements suggest a decline in processing sensory reafference

Sallard, Etienne ; Spierer, Lucas ; Ludwig, Catherine ; Deiber, Marie Pierre ; Barral, Jérôme

In: Experimental Brain Research, 2014, vol. 232, no. 2, p. 469–479

Deficits in the processing of sensory reafferences have been suggested as accounting for age-related decline in motor coordination. Whether sensory reafferences are accurately processed can be assessed based on the bimanual advantage in tapping: because of tapping with an additional hand increases kinesthetic reafferences, bimanual tapping is characterized by a reduced inter-tap interval...

Université de Fribourg

Posterior SMA Syndrome following subcortical stroke: Contralateral akinesia reversed by visual feedback

Radman, Narges ; Cacioppo, Stephanie ; Spierer, Lucas ; Schmidlin, Eric ; Mayer, Eugène ; Annoni, Jean-Marie

In: Neuropsychologia, 2013, vol. 51, no. 13, p. 2605–2610

Background: The supplementary motor area (SMA) plays a key role in motor programming and production and is involved in internally-cued movements. In neurological populations, SMA syndrome following a lesion to the “SMA proper” is characterized by transient impairment of voluntary movements and motor sequences. This syndrome is assumed to follow on from an interruption of the motor...

Université de Fribourg

Language context modulates reading route: an electrical neuroimaging study

Buetler, Karin A. ; Rodríguez, Diego de León ; Laganaro, Marina ; Müri, René ; Spierer, Lucas ; Annoni, Jean-Marie

In: Frontiers in Human Neuroscience, 2014, vol. 8, p. article 83

Introduction: The orthographic depth hypothesis (Katz and Feldman, 1983) posits that different reading routes are engaged depending on the type of grapheme/phoneme correspondence of the language being read. Shallow orthographies with consistent grapheme/phoneme correspondences favor encoding via non-lexical pathways, where each grapheme is sequentially mapped to its corresponding phoneme. In...

Université de Fribourg

Electrical neuroimaging during auditory motion aftereffects reveals that auditory motion processing is motion sensitive but not direction selective

Magezi, David A. ; Buetler, Karin A. ; Chouiter, Leila ; Annoni, Jean-Marie ; Spierer, Lucas

In: Journal of Neurophysiology, 2013, vol. 109, no. 2, p. 321-331

Following prolonged exposure to adaptor sounds moving in a single direction, participants may perceive stationary-probe sounds as moving in the opposite direction [direction-selective auditory motion aftereffect (aMAE)] and be less sensitive to motion of any probe sounds that are actually moving (motion-sensitive aMAE). The neural mechanisms of aMAEs, and notably whether they are due to...

Université de Fribourg

Auditory perceptual decision-making based on semantic categorization of environmental sounds

Lucia, Marzia De ; Tzovara, Athina ; Bernasconi, Fosco ; Spierer, Lucas ; Murray, Micah M.

In: NeuroImage, 2012, vol. 60, no. 3, p. 1704–1715

Discriminating complex sounds relies on multiple stages of differential brain activity. The specific roles of these stages and their links to perception were the focus of the present study. We presented 250 ms duration sounds of living and man-made objects while recording 160-channel electroencephalography (EEG). Subjects categorized each sound as that of a living, man-made or unknown item. We...

Université de Fribourg

Cognitive control of language production in bilinguals involves a partly independent process within the domain-general cognitive control network: Evidence from task-switching and electrical brain activity

Magezi, David A. ; Khateb, Asaid ; Mouthon, Michael ; Spierer, Lucas ; Annoni, Jean-Marie

In: Brain and Language, 2012, vol. 122, no. 1, p. 55–63

In highly proficient, early bilinguals, behavioural studies of the cost of switching language or task suggest qualitative differences between language control and domain-general cognitive control. By contrast, several neuroimaging studies have shown an overlap of the brain areas involved in language control and domain-general cognitive control. The current study measured both behavioural...

Université de Fribourg

Noise in brain activity engenders perception and influences discrimination sensitivity

Bernasconi, Fosco ; De Lucia, Marzia ; Tzovara, Athina ; Manuel, Aurelie L. ; Murray, Micah M. ; Spierer, Lucas

In: The Journal of Neuroscience, 2011, vol. 31, no. 49, p. 17971-17981

Behavioral and brain responses to identical stimuli can vary with experimental and task parameters, including the context of stimulus presentation or attention. More surprisingly, computational models suggest that noise-related random fluctuations in brain responses to stimuli would alone be sufficient to engender perceptual differences between physically identical stimuli. In two experiments...