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Université de Fribourg

Plastic modifications within inhibitory control networks induced by practicing a stop-signal task: an electrical neuroimaging study

Manuel, Aurelie L. ; Bernasconi, Fosco ; Spierer, Lucas

In: Cortex, 2012, p. -

Inhibitory control refers to our ability to suppress ongoing motor, affective or cognitive processes and mostly depends on a fronto–basal brain network. Inhibitory control deficits participate in the emergence of several prominent psychiatric conditions, including attention deficit/hyperactivity disorder or addiction. The rehabilitation of these pathologies might therefore benefit from...

Université de Fribourg

Progression of auditory discrimination based on neural decoding predicts awakening from coma

Tzovara, Athina ; Rossetti, Andrea O. ; Spierer, Lucas ; Grivel, Jeremy ; Murray, Micah M. ; Oddo, Mauro ; De Lucia, Marzia

In: Brain, 2013, vol. 136, no. 1, p. 81-89

Auditory evoked potentials are informative of intact cortical functions of comatose patients. The integrity of auditory functions evaluated using mismatch negativity paradigms has been associated with their chances of survival. However, because auditory discrimination is assessed at various delays after coma onset, it is still unclear whether this impairment depends on the time of the...

Université de Fribourg

inter- and intrahemispheric dissociations in ideomotor apraxia : a large-Scale lesion–symptom mapping study in subacute brain-damaged patients

Manuel, Aurelie L. ; Radman, Narges ; Mesot, Delphine ; Chouiter, Leila ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Cerebral Cortex, 2012, vol. 23, no. 12, p. 2781-2789

Pantomimes of object use require accurate representations of movements and a selection of the most task-relevant gestures. Prominent models of praxis, corroborated by functional neuroimaging studies, predict a critical role for left parietal cortices in pantomime and advance that these areas store representations of tool use. In contrast, lesion data points to the involvement of left inferior...

Université de Fribourg

Auditory perceptual decision-making based on semantic categorization of environmental sounds

Lucia, Marzia De ; Tzovara, Athina ; Bernasconi, Fosco ; Spierer, Lucas ; Murray, Micah M.

In: NeuroImage, 2012, vol. 60, no. 3, p. 1704–1715

Discriminating complex sounds relies on multiple stages of differential brain activity. The specific roles of these stages and their links to perception were the focus of the present study. We presented 250 ms duration sounds of living and man-made objects while recording 160-channel electroencephalography (EEG). Subjects categorized each sound as that of a living, man-made or unknown item. We...

Université de Fribourg

Cognitive control of language production in bilinguals involves a partly independent process within the domain-general cognitive control network: Evidence from task-switching and electrical brain activity

Magezi, David A. ; Khateb, Asaid ; Mouthon, Michael ; Spierer, Lucas ; Annoni, Jean-Marie

In: Brain and Language, 2012, vol. 122, no. 1, p. 55–63

In highly proficient, early bilinguals, behavioural studies of the cost of switching language or task suggest qualitative differences between language control and domain-general cognitive control. By contrast, several neuroimaging studies have shown an overlap of the brain areas involved in language control and domain-general cognitive control. The current study measured both behavioural...

Université de Fribourg

Noise in brain activity engenders perception and influences discrimination sensitivity

Bernasconi, Fosco ; De Lucia, Marzia ; Tzovara, Athina ; Manuel, Aurelie L. ; Murray, Micah M. ; Spierer, Lucas

In: The Journal of Neuroscience, 2011, vol. 31, no. 49, p. 17971-17981

Behavioral and brain responses to identical stimuli can vary with experimental and task parameters, including the context of stimulus presentation or attention. More surprisingly, computational models suggest that noise-related random fluctuations in brain responses to stimuli would alone be sufficient to engender perceptual differences between physically identical stimuli. In two experiments...