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Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis

Pföstl, Veronika von ; Li, Juan ; Zaldivar, Daniel ; Goense, Jozien ; Zhang, Xiaozhe ; Serr, Nadine ; Logothetis, Nikos K. ; Rauch, Alexander

In: NeuroImage, 2012, vol. 61, no. 1, p. 98–105

In contrast to the limited use of functional magnetic resonance imaging (fMRI) in clinical diagnostics, it is currently a mainstay of neuroimaging in clinical and basic brain research. However, its non-invasive use in combination with its high temporal and spatial resolution would make fMRI a perfect diagnostic tool. We are interested in whether a pharmacological challenge imposed on the brain...