Université de Fribourg

Organization of the Drosophila larval visual circuit

Larderet, Ivan ; Fritsch, Pauline ; Gendre, Nanae ; Maier, Larisa ; Fetter, Rick D. ; Schneider-Mizell, Casey ; Truman, James ; Zlatic, Marta ; Cardona, Albert ; Sprecher, Simon

Visual systems transduce, process and transmit light-dependent environmental cues. Computation of visual features depends on the types of photoreceptor neurons (PR) present, the organization of the eye and the wiring of the underlying neural circuit. Here, we describe the circuit architecture of the visual system of Drosophila larvae by mapping the synaptic wiring diagram and...

Université de Fribourg

Drosophila larvae establish appetitive olfactory memories via mushroom body neurons of embryonic origin

Pauls, Dennis ; Selcho, Mareike ; Gendre, Nanae ; Stocker, Reinhard F. ; Thum, Andreas S.

In: The Journal of Neuroscience, 2010, vol. 30, no. 32, p. 10655-10666

Insect mushroom bodies are required for diverse behavioral functions, including odor learning and memory. Using the numerically simple olfactory pathway of the Drosophila melanogaster larva, we provide evidence that the formation of appetitive olfactory associations relies on embryonic-born intrinsic mushroom body neurons (Kenyon cells). The participation of larval-born Kenyon cells, i.e.,...