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A new procyanidin B from Campylospermum zenkeri (Ochnaceae) and antiplasmodial activity of two derivatives of (±)-serotobenine

Mbabi Nyemeck II, Norbert ; Ngono Bikobo, Dominique Serge ; Zintchem, Auguste Abouem A. ; Schäfer, Eva-Maria ; Bochet, Christian G. ; Pegnyemb, Dieudonné Emmanuel ; Koert, Ulrich

In: Natural Product Research, 2017, vol. 31, no. 24, p. 2875-2884

Phytochemical investigation of the stem bark of Campylospermum zenkeri led to the isolation of five known compounds: (Z,Z)-9,12-octadecadienoic acid (1), serotobenine (2), agathisflavone (3), lophirone A (4) and lophirone F (5), together with a new derivative of procyanidin B, a catechin dimer named zenkerinol (6). Serotobenine (2) is structurally related to decursivine which shows moderate...