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In vitro biocompatibility of new silver(I) coordination compound coated-surfaces for dental implant applications

Brunetto, Priscilla S. ; Slenters, Tünde Vig ; Fromm, Katharina M.

In: Materials, 2011, vol. 4, no. 2, p. 355-367

Biofilm formation on implant materials causes a common problem: resistance to aggressive pharmacological agents as well as host defenses. Therefore, to reduce bacterial adhesion to implant surfaces we propose to use silver(I) coordination networks as it is known that silver is the most powerful antimicrobial inorganic agent. As a model surface, self-assembled monolayers (SAMs) on gold Au(111) was...

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Silver nanoparticle formation in different sizes induced by peptides identified within split-and-mix libraries

Belser, Kirsten ; Slenters, Tünde Vig ; Pfumbidzai, Conelious ; Upert, Grégory ; Mirolo, Laurent ; Fromm, Katharina M. ; Wennemers, Helma

In: Angewandte Chemie International Edition, 2009, vol. 48, no. 20, p. 3661-3664

Split-and-mix libraries are an excellent tool for the identification of peptides that induce the formation of Ag nanoparticles in the presence of either light or sodium ascorbate to reduce Ag+ ions. Structurally diverse peptides were detected in colorimetric on-bead screenings that generate Ag nanoparticles of different sizes, as confirmed by SEM and X-ray powder diffraction studies

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