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    Université de Fribourg

    Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery

    Heidegger, Simon ; Gößl, Dorothée ; Schmidt, Alexandra ; Niedermayer, Stefan ; Argyo, Christian ; Endres, Stefan ; Bein, Thomas ; Bourquin, Carole

    In: Nanoscale, 2015, vol. 8, no. 2, p. 938–948

    Multifunctional mesoporous silica nanoparticles (MSN) have attracted substantial attention with regard to their high potential for targeted drug delivery. For future clinical applications it is crucial to address safety concerns and understand the potential immunotoxicity of these nanoparticles. In this study, we assess the biocompatibility and functionality of multifunctional MSN in freshly...