Université de Neuchâtel

Boophiline, an Antimicrobial Sterol Amide from the Cattle Tick Boophilus microplus

Potterat, Olivier ; Hostettmann, Kurt ; Höltzel, Alexandra ; Jung, Günther ; Diehl, Peter A. ; Petrini, Orlando

In: Helvetica Chimica Acta, 1997, vol. 80, no. 7, p. 2066-2072

Boophiline (1), a new sterol amide was isolated from the cattle tick Boophilus microplus (Ixodidae). The structure was assigned as N-[3-(sulfooxy)-25ξ-cholest-5-en-26-oyl]-L-isoleucine by detailed 2D NMR investigations in conjunction with FAB mass spectrometry and acidic hydrolyses. Complete assignment of the diastereotopic methylene protons of the ring system could be deduced from...