Université de Fribourg

Responsive nanofibers with embedded hierarchical lipid self-assemblies

Tien, Nguyen D. ; Maurya, Anjani K. ; Fortunato, Giuseppino ; Rottmar, Markus ; Zboray, Robert ; Erni, Rolf ; Dommann, Alex ; Rossi, René M. ; Neels, Antonia ; Sadeghpour, Amin

In: Langmuir, 2020, vol. 36, no. 40, p. 11787–11797

We introduce the design and study of a hybrid electrospun membrane with a dedicated nanoscale structural hierarchy for controlled functions in the biomedical domain. The hybrid system comprises submicrometer-sized internally self-assembled lipid nanoparticles (ISAsomes or mesosomes) embedded into the electrospun membrane with a nanofibrous polymer network. The internal structure of ISAsomes, ...

Université de Fribourg

Structural insights into semicrystalline states of electrospun nanofibers: a multiscale analytical approach

Maurya, Anjani K. ; Weidenbacher, Lukas ; Spano, Fabrizio ; Fortunato, Giuseppino ; Rossi, René M. ; Frenz, Martin ; Dommann, Alex ; Neels, Antonia ; Sadeghpour, Amin

In: Nanoscale, 2019, vol. 11, no. 15, p. 7176–7187

A dedicated nanofiber design for applications in the biomedical domain is based on the understanding of nanofiber structures. The structure of electrospun nanofibers strongly influences their properties and functionalities. In polymeric nanofibers X-ray scattering and diffraction methods, i.e. SAXS and WAXD, are capable of decoding their structural insights from about 100 nm down to the...