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Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

Smets, Bart ; Ghillebert, Ruben ; Snijder, Pepijn De ; Binda, Matteo ; Swinnen, Erwin ; De Virgilio, Claudio ; Winderickx, Joris

In: Current Genetics, 2010, vol. 56, no. 1, p. 1-32

Cells of all living organisms contain complex signal transduction networks to ensure that a wide range of physiological properties are properly adapted to the environmental conditions. The fundamental concepts and individual building blocks of these signalling networks are generally well-conserved from yeast to man; yet, the central role that growth factors and hormones play in the regulation of...