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The effect of parvalbumin deficiency on the acoustic startle response and prepulse inhibition in mice

Popelář, Jiří ; Rybalko, Natalia ; Burianová, Jana ; Schwaller, Beat ; Syka, Josef

In: Neuroscience Letters, 2013, vol. 553, p. 216–220

The strength of the acoustic startle response (ASR) to short bursts of broadband noise or tone pips (4, 8 and 16 kHz) and the prepulse inhibition (PPI) of the ASR elicited by prepulse tones (4, 8 and 16 kHz) were measured in parvalbumin-deficient (PV−/−) mice and in age-matched PV+/+ mice as controls. Hearing thresholds as determined from recordings of auditory brainstem responses were found...