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Identification of cis- and trans-acting elements regulating calretinin expression in mesothelioma cells

Kresoja-Rakic, Jelena ; Kapaklikaya, Esra ; Ziltener, Gabriela ; Dalcher, Damian ; Santoro, Raffaella ; Christensen, Brock C. ; Johnson, Kevin C. ; Schwaller, Beat ; Weder, Walter ; Stahel, Rolf A. ; Felley-Bosco, Emanuela

In: Oncotarget, 2016, vol. 7, no. 16, p. 21272–21286

Calretinin (CALB2) is a diagnostic marker for epithelioid mesothelioma. It is also a prognostic marker since patients with tumors expressing high calretinin levels have better overall survival. Silencing of calretinin decreases viability of epithelioid mesothelioma cells. Our aim was to elucidate mechanisms regulating calretinin expression in mesothelioma. Analysis of calretinin transcript...