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Scan without evidence of dopaminergic deficit: A 10-year retrospective study

Nicastro, Nicolas ; Garibotto, Valentina ; Badoud, Simon ; Burkhard, Pierre R.

In: Parkinsonism & Related Disorders, 2016, vol. 31, p. 53–58

123I-ioflupane SPECT is a powerful method to assess nigrostriatal dopamine system integrity. Several independent studies have shown that 1–15% of patients with suspected degenerative parkinsonism, mainly PD, have scans without evidence of dopaminergic deficit (SWEDD). It has been proposed that most SWEDD patients either present with a non-degenerative condition mimicking PD, such as...