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Université de Fribourg

Room-temperature spin crossover and Langmuir–Blodgett film formation of an iron(II) triazole complex featuring a long alkyl chain substituent: the tail that wags the dog

Kitchen, Jonathan A. ; White, Nicholas G. ; Gandolfi, Claudio ; Albrecht, Martin ; Jameson, Guy N. L. ; Tallon, Jeffery L. ; Brooker, Sally

In: Chemical Communications, 2010, vol. 46, no. 35, p. 6464-6466

[FeII(C₁₆dpt)₂(NCS)₂]·⅔H₂O displays temperature-mediated spin crossover (SCO) with T½ = 290 K and the long alkyl chain substituent on the dipyridyltriazole ligand facilitates the formation of a stable Langmuir–Blodgett film at an air–water interface.

Université de Fribourg

Silver coordination polymers for prevention of implant infection: thiol interaction, impact on respiratory chain enzymes, and hydroxyl radical induction

Gordon, Oliver ; Slenters, Tünde Vig ; Brunetto, Priscilla S. ; Villaruz, Amer E. ; Sturdevant, Daniel E. ; Otto, Michael ; Landmann, Regine ; Fromm, Katharina M.

In: Antimicrobial Agents and Chemotherapy, 2010, vol. 54, no. 10, p. 4208-4218

Prosthetic joint replacements are used increasingly to alleviate pain and improve mobility of the progressively older and more obese population. Implant infection occurs in about 5% of patients and entails significant morbidity and high social costs. It is most often caused by staphylococci, which are introduced perioperatively. They are a source of prolonged seeding and difficult to treat...

Université de Fribourg

Structural and electronic properties of isostructural transition metal nitrides

Sahnoun, Mohammed ; Parlebas, J.C. ; Driz, Mohamed ; Daul, Claude A.

In: Physica B: Condensed Matter, 2010, no. 18, p. 3822-3825

The structural and electronic properties of three isostructural transition metal nitrides VN, NbN and TaN have been calculated using the full-potential linearized augmented plane-wave method within a generalized gradient approximation scheme for the exchange-correlation potential. Perfect NaCl structures as well as lattices containing nitrogen vacancies (M₄N₃), and an hexagonal ε-M₂N...

Université de Fribourg

Different Mi-2 Complexes for Various Developmental Functions in Caenorhabditis elegans

Passannante, Myriam ; Marti, Claude-Olivier ; Pfefferli, Catherine ; Moroni, Paolo S. ; Kaeser-Pebernard, Stéphanie ; Puoti, Alessandro ; Hunziker, Peter ; Wicky, Chantal ; Müller, Fritz

In: PLoS ONE, 2010, vol. 5, no. 10, p. e13681

Biochemical purifications from mammalian cells and Xenopus oocytes revealed that vertebrate Mi-2 proteins reside in multisubunit NuRD (Nucleosome Remodeling and Deacetylase) complexes. Since all NuRD subunits are highly conserved in the genomes of C. elegans and Drosophila, it was suggested that NuRD complexes also exist in invertebrates. Recently, a novel dMec complex, composed of dMi-2 and...

Université de Fribourg

Phosphate systemically inhibits development of arbuscular mycorrhiza in Petunia hybrida and represses genes involved in mycorrhizal functioning

Breuillin, Florence ; Schramm, Jonathan ; Hajirezaei, Mohammad ; Ahkami, Amir ; Favre, Patrick ; Druege, Uwe ; Hause, Bettina ; Bucher, Marcel ; Kretzschmar, Tobias ; Bossolini, Eligio ; Kuhlemeier, Cris ; Martinoia, Enrico ; Franken, Philipp ; Scholz, Uwe ; Reinhardt, Didier

In: The Plant Journal, 2010, p. -

Most terrestrial plants form arbuscular mycorrhiza (AM), mutualistic associations with soil fungi of the order Glomeromycota. The obligate biotrophic fungi trade mineral nutrients, mainly phosphate (Pi), for carbohydrates from the plants. Under conditions of high exogenous phosphate supply, when the plant can meet its own P requirements without the fungus, AM are suppressed,...

Université de Fribourg

Desynchronization of neocortical networks by asynchronous release of GABA at autaptic and synaptic contacts from fast-spiking interneurons

Manseau, Frédé ric ; Marinelli, Silvia ; Méndez, Pablo ; Schwaller, Beat ; Prince, David A. ; Huguenard, John R. ; Bacci, Alberto

In: PLoS Biology, 2010, vol. 8, no. 9, p. e1000492

Networks of specific inhibitory interneurons regulate principal cell firing in several forms of neocortical activity. Fast-spiking (FS) interneurons are potently self-inhibited by GABAergic autaptic transmission, allowing them to precisely control their own firing dynamics and timing. Here we show that in FS interneurons, high-frequency trains of action potentials can generate a delayed and...

Université de Fribourg

The phylogeography of an alpine leaf beetle: Divergence within Oreina elongata spans several ice ages

Borer, Matthias ; Alvarez, Nadir ; Buerki, Sven ; Margraf, Nicolas ; Rahier, Martine ; Naisbit, Russell E.

In: Molecular Phylogenetics and Evolution, 2010, vol. 57, no. 2, p. 703-709

The genetic landscape of the European flora and fauna was shaped by the ebb and flow of populations with the shifting ice during Quaternary climate cycles. While this has been well demonstrated for lowland species, less is known about high altitude taxa. Here we analyze the phylogeography of the leaf beetle Oreina elongata from 20 populations across the Alps and Apennines. Three mitochondrial and...

Université de Fribourg

The C. elegans Hox gene ceh-13 regulates cell migration and fusion in a non-colinear way. Implications for the early evolution of Hox clusters

Tihanyi, Borbála ; Vellai, Tibor ; Regős, Ágnes ; Ari, Eszter ; Müller, Fritz ; Takács-Vellai, Krisztina

In: BMC Developmental Biology, 2010, vol. 10, no. 78, p. 78

Background: Hox genes play a central role in axial patterning during animal development. They are clustered in the genome and specify cell fate in sequential domains along the anteroposterior (A-P) body axis in a conserved order that is co-linear with their relative genomic position. In the soil worm Caenorhabditis elegans, this striking rule of co-linearity is broken by the anterior Hox gene...

Université de Fribourg

Polymorphism of postmating reproductive isolation within plant species

Scopece, Giovanni ; Lexer, Christian ; Widmer, Alex ; Cozzolino, Salvatore

In: Taxon, 2010, vol. 59, no. 5, p. 1367-1374

Speciation can be viewed as the evolution of reproductive isolation between formerly interbreeding populations. Recent years have seen great advances in our understanding of the genetic mechanisms underlying postmating reproductive isolation during plant speciation. Nevertheless, little is known about the early stages of species divergence and the evolution of reproductive isolation at the...