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Université de Fribourg

Time course of cardiovascular responses induced by mental and orthostatic challenges

Lackner, Helmut Karl ; Goswami, Nandu ; Papousek, Ilona ; Roessler, Andreas ; Grasser, Erik Konrad ; Montani, Jean-Pierre ; Jezova, Daniela ; Hinghofer-Szalkay, Helmut

In: International Journal of Psychophysiology, 2010, vol. 75, no. 1, p. 48-53

Cardiovascular responses to single stressors diminish over time. Interaction of different stressors influencing hemodynamic variables, indicative of stress-induced reactivity and physiological responses are, however, poorly understood. We investigated time course of mental (using mental arithmetic, MA) and orthostatic (using head up tilt, HUT) challenges induced responses in 16 males. Three...

Université de Fribourg

Fermeture d’une bibliothèque et avenir de ses collections : le cas de la bibliothèque de l’Institut de Formation des Maîtres et Maîtresses de l'Enseignement Secondaire (IFMES) à Genève

d’Espine, Emmanuelle ; Scariati, Renato (Dir.)

Mémoire de Certificate of Advanced Studies (CAS) : Université de Fribourg, 2009.

Le travail suivant analyse la gestion de la fermeture d’une bibliothèque et les critères des choix de la destination du fonds : proposition des ouvrages à d’autres bibliothèques qui héritent du public cible ou décision de désherbage. La présentation de l’histoire, la mission, les publics et la nature des collections de la bibliothèque de l’Institut de Formation des Maîtres et...

Université de Fribourg

Rate of cardiovascular recovery to combined or separate orthostatic and mental challenges

Goswami, Nandu ; Lackner, Helmut Karl ; Papousek, Ilona ; Jezova, Daniela ; Hinghofer-Szalkay, Helmut ; Montani, Jean-Pierre

In: International Journal of Psychophysiology, 2010, vol. 75, no. 1, p. 54-62

Post stress neurovascular responses induced by physical and mental stress are poorly understood. We investigated the time course of cardiovascular and autonomic recovery, induced by orthostatic and mental challenge, using passive head up tilt (HUT) and mental arithmetic (MA), respectively, when applied singly (MA, HUT) or in combination (MA + HUT). Fifteen healthy males participated in three...

Université de Fribourg

Le métier de bibliothécaire spécialiste en perspectives

Cantinotti, Andrea ; Thiébaud, Marc (Dir.) ; Frey, Jeannette (Codir.)

Mémoire de Certificate of Advanced Studies (CAS) : Université de Fribourg, 2009.

Que sera le métier de bibliothécaire spécialiste à l’avenir ? Voilà résumé très brièvement le sujet de ce travail de mémoire. Avec l’arrivée massive ’Internet dans tous les domaines de l’information, les bibliothécaires sont questionnés dans leur identité profonde, jusqu’à la remise en cause de leur utilité. Ce mémoire de formation continue a pour but de revisiter la...

Université de Fribourg

Role of mutation of the circadian clock gene Per2 in cardiovascular circadian rhythms

Vukolic, Ana ; Antic, Vladan ; Vliet, Bruce N. Van ; Yang, Zhihong ; Albrecht, Urs ; Montani, Jean-Pierre

In: American Journal of Physiology Regulatory, Integrative and Comparative Physiolology, 2010, p. -

Alterations in the circadian blood pressure pattern are frequently observed in hypertension and lead to increased cardiovascular morbidity. However, there are no studies that have investigated a possible implication of the Period2 gene, a key component of the molecular circadian clock, on the circadian rhythms of blood pressure and heart rate. To address this question, we monitored blood...

Université de Fribourg

Interaction of mental and orthostatic stressors

Goswami, Nandu ; Lackner, Helmut K. ; Papousek, Ilona ; Jezova, Daniela ; Montani, Jean-Pierre ; Hinghofer-Szalkay, Helmut G.

In: Acta Astronautica, 2010, p. -

We assessed hemodynamic responses induced by orthostatic and mental stressors, using passive head up tilt (HUT) and mental arithmetic (MA), respectively. The 15 healthy males underwent three protocols: (1) HUT alone, (2) MA in supine position and (3) MA+HUT, with sessions randomized and ≥2 weeks apart. In relation to baseline, HUT increased heart rate (HR) (+20.4±7.1 bpm; p<0.001),...

Université de Fribourg

Spatial relational learning and memory abilities do not differ between men and women in a real-world, open-field environment

Banta Lavenex, Pamela A. ; Lavenex, Pierre

In: Behavioural Brain Research, 2010, vol. 207, no. 1, p. 125-137

This study assesses gender differences in spatial and non-spatial relational learning and memory in adult humans behaving freely in a real-world, open-field environment. In Experiment 1, we tested the use of proximal landmarks as conditional cues allowing subjects to predict the location of rewards hidden in one of two sets of three distinct locations. Subjects were tested in two different...

Université de Fribourg

Developmental regulation of gene expression and astrocytic processes may explain selective hippocampal vulnerability

Lavenex, Pierre ; Sugden, Steven G. ; Davis, Ryan R. ; Gregg, Jeffrey P. ; Lavenex, Pamela Banta

In: Hippocampus, 2010, p. -

The hippocampus plays a central role in the brain network that is essential for memory function. Paradoxically, the hippocampus is also the brain structure that is most sensitive to hypoxic-ischemic episodes. Here, we show that the expression of genes associated with glycolysis and glutamate metabolism in astrocytes and the coverage of excitatory synapses by astrocytic processes undergo...

Université de Fribourg

Driving ribosome assembly

Kressler, Dieter ; Hurt, Ed ; Baβler, Jochen

In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010, p. -

Ribosome biogenesis is a fundamental process that provides cells with the molecular factories for cellular protein production. Accordingly, its misregulation lies at the heart of several hereditary diseases (e.g., Diamond-Blackfan anemia). The process of ribosome assembly comprises the processing and folding of the pre-rRNA and its concomitant assembly with the ribosomal proteins. Eukaryotic...

Université de Fribourg

Neuroendocrine characterization and anorexigenic effects of telmisartan in diet- and glitazone-induced weight gain

Aubert, Gregory ; Burnier, Michel ; Dulloo, Abdul G. ; Perregaux, Christine ; Mazzolai, Lucia ; Pralong, François ; Zanchi, Anne

In: Metabolism - Clinical and Experimental, 2010, vol. 59, no. 1, p. 25-32

Telmisartan is an angiotensin II receptor blocker with peroxisome proliferator–activated receptor–γ agonistic properties. Telmisartan prevents weight gain and decreases food intake in models of obesity and in glitazone-treated rodents. This study further investigates the influence of telmisartan and pioglitazone and their association on weight gain and body composition by examining...