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Université de Fribourg

Spatial relational memory in 9-month-old macaque monkeys

Lavenex, Pierre ; Lavenex, Pamela Banta

In: Learning & Memory, 2006, vol. 13, p. 84-96

This experiment assesses spatial and nonspatial relational memory in freely moving 9-mo-old and adult (11-13-yr-old) macaque monkeys (Macaca mulatta). We tested the use of proximal landmarks, two different objects placed at the center of an open-field arena, as conditional cues allowing monkeys to predict the location of food rewards hidden in one of two sets of three distinct locations....

Université de Fribourg

Hippocampal lesion prevents spatial relational learning in adult Macaque monkeys

Lavenex, Pamela Banta ; Amaral, David G. ; Lavenex, Pierre

In: The Journal of Neuroscience, 2006, vol. 26(17), p. 4546-4558

The role of the hippocampus in spatial learning and memory has been extensively studied in rodents. Comparable studies in nonhuman primates, however, are few, and findings are often contradictory. This may be attributable to the failure to distinguish between allocentric and egocentric spatial representations in experimental designs. For this experiment, six adult monkeys received bilateral...

Université de Fribourg

Corticotropin-Releasing Hormone directly stimulates thermogenesis in skeletal muscle possibly through substrate cycling between de novo lipogenesis and lipid oxidation

Solinas, Giovanni ; Summermatter, Serge ; Mainieri, Davide ; Gubler, Marcel ; Montani, Jean-Pierre ; Seydoux, Josiane ; Smith, S. R. ; Dulloo, Abdul G.

In: Endocrinology, 2006, vol. 147(1), p. 31-38

The mechanisms by which CRH and related peptides (i.e. the CRH/urocortin system) exert their control over thermogenesis and weight regulation have until now focused only upon their effects on brain centers controlling sympathetic outflow. Using a method that involves repeated oxygen uptake determinations in intact mouse skeletal muscle, we report here that CRH can act directly on skeletal...

Université de Fribourg

Interventions : une étude expérimentale et analogue de différentes formes d'interventions

Montini Lirrg, Patrizia ; Reicherts, Michaël (Dir.) ; Perrez, Meinrad (Codir.)

Thèse de doctorat : Université de Fribourg, 2005.

Cette étude est réalisée dans le cadre de la recherche sur les processus psychothérapeutiques et leurs effets, en fonction de différentes formes d’interventions approfondissantes. De plus, elle tient compte des caractéristiques préalables du client susceptibles de modérer l’impact cognitif et émotionnel de ces interventions. Dans cette étude expérimentale et analogue, on applique...

Université de Fribourg

Regulation of fat storage via suppressed thermogenesis: a thrifty phenotype that predisposes individuals with catch-up growth to insulin resistance and obesity

Dulloo, Abdul G.

In: Hormone Research, 2006, vol. 65(suppl 3), p. 90–97

Catch-up growth during infancy and childhood is increasingly recognized as a major risk factor for later development of insulin-related complications and chronic diseases, namely abdominal obesity, type 2 diabetes and cardiovascular disease. As catch-up growth per se is characterized by insulin resistance, hyperinsulinaemia and an accelerated rate of fat storage (i.e., catch-up fat) even in the...

Université de Fribourg

Double 1s shell ionization of Si induced in collisions with 1–3-MeV protons

Kavčič, Matjaz ; Tökési, K.

In: Physical Review A, 2005, vol. 72, p. 062704

The double 1s ionization of Si induced in collisions with protons was studied by measuring the K x-ray emission of a solid Si target ionized by the impact of 1–3-MeV protons. In order to resolve the hypersatellite contributions corresponding to the radiative decay of the double 1s vacancy state, a high-resolution crystal spectrometer was employed yielding sub-eV energy...

Université de Fribourg

A sound card based multi-channel frequency measurement system

Groeger, Stephan ; Bison, Georg ; Knowles, Paul E. ; Weis, Antoine

In: The European Physical Journal: Applied Physics, 2006, vol. 33, p. 221-224

For physical processes which express themselves as a frequency, for example magnetic field measurements using optically-pumped alkali-vapor magnetometers, the precise extraction of the frequency from the noisy signal is a classical problem. We describe herein a frequency measurement system based on an inexpensive commercially available computer sound card coupled with a software single-tone...