In: The Journal of Physical Chemistry, 2012, vol. 116, no. 41, p. 10203–10208
High-level G3X(MP2)-RAD calculations have been carried out to examine the effect of interposing a “connector” group (W) on the interaction between a substituent (X) and the radical center in carbon-centered radicals (•CH₂–W–X). The connector groups include −CH₂–, −CH═CH–, −C≡C–, −p-C₆H₄–, −m-C₆H₄–, and −o-C₆H₄–,...
|
In: Mots médiévaux offerts à Ruedi Imbach, 2011, p. 67-76
|
In: Proceedings of the National Academy of Sciences of the United States of America - PNAS, 2012, vol. 109, no. 42, p. 16882-16887
Sterols and related membrane-perturbing agents are subject to a quality control cycle. Compounds that fail to pass this control are acetylated and secreted into the culture media, whereas lipids that pass the cycle are deacetylated and retained within the cell. Here we describe the identification of a family of conserved proteins, the Pathogen-Related Yeast (PRY) proteins, as a class of...
|
In: New Phytologist, 2012, vol. 196, no. 3, p. 652–654
|
In: Science, 2012, vol. 338, no. 6107, p. 666-671
Ribosomal proteins are synthesized in the cytoplasm, before nuclear import and assembly with ribosomal RNA (rRNA). Little is known about coordination of nucleocytoplasmic transport with ribosome assembly. Here, we identify a transport adaptor, symportin 1 (Syo1), that facilitates synchronized coimport of the two 5S-rRNA binding proteins Rpl5 and Rpl11. In vitro studies revealed that Syo1...
|
In: PLoS ONE, 2012, vol. 7, no. 10, p. e47518
The Drosophila larva has turned into a particularly simple model system for studying the neuronal basis of innate behaviors and higher brain functions. Neuronal networks involved in olfaction, gustation, vision and learning and memory have been described during the last decade, often up to the single-cell level. Thus, most of these sensory networks are substantially defined, from the sensory...
|
In: Aquatic Ecology, 2012, vol. 46, no. 4, p. 487-499
The development of a community through time, or succession, is generally described as the orderly replacement of species until a deterministic, stable endpoint is reached. However, stochastic factors, coupled with intrinsic biotic factors, such as herbivory or predation, can cause communities within the same habitat to become highly dissimilar in composition. Much research on the succession of...
|
In: Biochemical Journal, 2012, vol. 447, p. 103–114
The hydrolysis of ceramides in yeast is catalysed by the alkaline ceramidases Ypc1p and Ydc1p, two highly homologous membrane proteins localized to the ER (endoplasmic reticulum). As observed with many enzymes, Ypc1p can also catalyse the reverse reaction, i.e. condense a non-esterified fatty acid with PHS (phytosphingosine) or DHS (dihydrosphingosine) and thus synthesize ceramides. When...
|
In: International Journal of Bifurcation and Chaos, 2012, vol. 22, no. 07, p. 1250166
The past few years have witnessed the great success of a new family of paradigms, social tagging networks, which allows users to freely associate social tags to items and efficiently manage them. Thus it provides us a promising way to effectively find useful and interesting information. In this paper, we consider two typical roles of social tags: (i) an accessorial tool helping users organize...
|
In: Physica A: Statistical Mechanics and its Applications, 2012, vol. 139, no. 22, p. 5769–5778
To evaluate the performance of prediction of missing links, the known data are randomly divided into two parts, the training set and the probe set. We argue that this straightforward and standard method may lead to terrible bias, since in real biological and information networks, missing links are more likely to be links connecting low-degree nodes. We therefore study how to uncover missing links...
|
